Başlık için Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 193, listelenen: 91-110
-
Gene variants and serum levels of synaptic vesicle and presynaptic plasma membrane proteins in alcohol dependence and their relationship with impulsivity and temperament
(UNIV SAOPAULO, 2021)Background: Exocytosis-related gene variants have been suggested to be associated with externalizing behaviors. Objective: This study aimed to examine VAMP2 26 bp Ins\Del, synaptotagmin XI (Syt11) rs3820594 and 33-bp ... -
Ghrelin may reduce radiation-induced mucositis and anorexia in head-neck cancer
(Churchill Livingstone, 2007)Body weight toss is common in cancer patients, and is often associated with poor prognosis, it greatly impairs quality of life (QOL). Radiation therapy (RT) is used in head and neck cancers (HNC) either as a primary treatment ... -
GPR30 Gene Polymorphisms Are Associated with Gynecomastia Risk in Adolescents
(Karger, 2015)Aim: The G protein-coupled receptor, GPR30, which is a third estrogen receptor, has been shown to mediate estrogenic effects on the essential features of human breast cancer cells. The aim of this study was to evaluate the ... -
The Healing Effect of Digoxin on Peripheral Nerve Damage and Its Relation to IL-17/IL-10
(Turkish Neurosurgical Society, 2023)AIM: To demonstrate the curative effect of digoxin on peripheral nerve damage with its anti-inflammatory role on interleukin (IL)-17. MATERIAL and METHODS: The study was conducted with 30 male Sprague Dawley albino mature ... -
Homozygous Ala65Pro Mutation with V89L Polymorphism in SRD5A2 Deficiency
(Galenos Yayincilik, 2016)Objective: Deficiency of steroid 5-alpha reductase type 2 (5 alpha RD2) is a rare autosomal recessive disorder caused by mutations in the SRD5A2 gene. A defect in the 5-alpha reductase enzyme, which ensures conversion of ... -
Hydroquinidine displays a significant anticarcinogenic activity in breast and ovarian cancer cells via inhibiting cell-cycle and stimulating apoptosis
(TUBITAK, 2023)Breast and ovarian cancers are women’s most commonly diagnosed cancers. Seeking an efficient anticarcinogenic compound is still a top priority regarding the aggressiveness of these cancers and the limited benefit of current ... -
Hydroxychloroquine/azithromycin treatment, QT interval and ventricular arrhythmias in hospitalised patients with COVID-19
(Wiley, 2021)Hydroxychloroquine (HCQ) and azithromycin (AZM) are widely used in off‐label treatment of novel coronavirus disease (COVID‐19). However, cardiac safety of these drugs is still controversial in COVID‐19. Therefore, we aimed ... -
Identifying Potential miRNA Biomarkers for Gastric Cancer Diagnosis Using Machine Learning Variable Selection Approach
(Frontiers Media S.A., 2022)Aim: This study aimed to accurately identification of potential miRNAs for gastric cancer (GC) diagnosis at the early stages of the disease. Methods: We used GSE106817 data with 2,566 miRNAs to train the machine learning ... -
Immunohistochemical Distribituon of COX-1, COX-2, and TGF beta-1 in the Duodenum of Rats Treated with Capsaicin
(Kafkas Univ, Veteriner Fakultesi Dergisi, 2016)The purpose of this study was to investigate the effects of capsaicin on the duodenal distribution of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and Transforming growth factor beta-1 (TGF beta-1) in rats. Rats were ... -
Impact of caffeic acid phenethyl ester treatment on vancomycin-induced pancreatic damage in rats
(Sage Publications Inc, 2016)This study investigates the preventive effect of caffeic acid phenethyl ester (CAPE) on pancreatic damage induced by vancomycin (VCM) in rats. Rats were equally divided into three groups: group I (control), group II (only ... -
The impact of gender and academic achievement on the violation of academic integrity for medical faculty students, a descriptive cross-sectional survey study
(Bmc, 2019)Purpose: The aim of this study is to determine the characteristics of medical faculty students about violations of academic integrity. Method: From the whole population of the 572 students of the Mugla Sitki Kocman University ... -
Important milestones for cancer at the Nobel prize
(Wolters Kluwer Medknow Publications, 2020)The Nobel Prize, which is awarded annually, is open to everyone, regardless of nationality, race, belief or ideology, and winners are announced in October. We evaluated the history of the Nobel prizes for awards that have ... -
The Important Witness of the Malaria Struggle in Turkey: Milasli Ismail Hakki and His Pamphlet Entitled "Who Knows What About Malaria?"
(Duzce Univ, 2018)Objective: One of the malaria struggle methods in Turkey was informing public and professionals by publications. The aim of this study was to assess malaria struggle works at first years of the Turkish republician era in ... -
In vitro anti-carcinogenic effect of andarine as a selective androgen receptor modulator on MIA-PaCa-2 cells by decreased proliferation and cell-cycle arrest at G0/G1 phase
(Elsevier Ltd, 2023)Pancreatic cancer (PC) continues to be devastating due to its highly malignant nature and poor prognosis. The limited benefits of the chemotherapeutic drugs and increasing resistance pose a critical challenge to overcome ... -
In Vitro Effects of Propofol on Cytotoxic, Apoptotic and PI3K-Akt Signaling Pathway Genes on Brain Cancer Cells
(Bentham Science, 2021)Aim: It was aimed to determine the cytotoxic and apoptotic effect of propofol on glioma cells. Background: Propofol [2,6-diisopropylphenol] is a commonly used intravenous anesthetic. Propofol is known to have a mechanism ... -
Influence of Pinealectomy and Long-term Melatonin Administration on Inflammation and Oxidative Stress in Experimental Gouty Arthritis
(Springer, 2022)Gout is an inflammatory arthritis characterized by the deposition of monosodium urate (MSU) crystals in the joints or soft tissue. MSU crystals are potent inflammation inducers. Melatonin (MLT) is a powerful endogenous ... -
Integrative Analysis of Axolotl Gene Expression Data from Regenerative and Wound Healing Limb Tissues
(Nature Research, 2019)Axolotl (Ambystoma mexicanum) is a urodele amphibian endowed with remarkable regenerative capacities manifested in scarless wound healing and restoration of amputated limbs, which makes it a powerful experimental model for ... -
Investigation of effects of short-term exposure to 50HZ magnetic field on central, peripheral, and autonomic nervous systems in rats
(Wiley-Blackwell, 2015)Although a large number of exposure studies have been carried out to investigate possible detrimental effects of a power-line frequency magnetic field (PF-MF; 50-60Hz) on living organisms, there is no consensus in reported ... -
Investigation of genetic variations of IL17 for vitiligo disease
(Kuwait Medical Assoc, 2019)Objective: Vitiligo is a disorder of pigmentation characterized by the presence of depigmented skin macules due to a chronic and progressive loss of melanocytes from the cutaneous epidermis. Among many different etiologic ...