Başlık için Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 193, listelenen: 103-122
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The Important Witness of the Malaria Struggle in Turkey: Milasli Ismail Hakki and His Pamphlet Entitled "Who Knows What About Malaria?"
(Duzce Univ, 2018)Objective: One of the malaria struggle methods in Turkey was informing public and professionals by publications. The aim of this study was to assess malaria struggle works at first years of the Turkish republician era in ... -
In vitro anti-carcinogenic effect of andarine as a selective androgen receptor modulator on MIA-PaCa-2 cells by decreased proliferation and cell-cycle arrest at G0/G1 phase
(Elsevier Ltd, 2023)Pancreatic cancer (PC) continues to be devastating due to its highly malignant nature and poor prognosis. The limited benefits of the chemotherapeutic drugs and increasing resistance pose a critical challenge to overcome ... -
In Vitro Effects of Propofol on Cytotoxic, Apoptotic and PI3K-Akt Signaling Pathway Genes on Brain Cancer Cells
(Bentham Science, 2021)Aim: It was aimed to determine the cytotoxic and apoptotic effect of propofol on glioma cells. Background: Propofol [2,6-diisopropylphenol] is a commonly used intravenous anesthetic. Propofol is known to have a mechanism ... -
Influence of Pinealectomy and Long-term Melatonin Administration on Inflammation and Oxidative Stress in Experimental Gouty Arthritis
(Springer, 2022)Gout is an inflammatory arthritis characterized by the deposition of monosodium urate (MSU) crystals in the joints or soft tissue. MSU crystals are potent inflammation inducers. Melatonin (MLT) is a powerful endogenous ... -
Integrative Analysis of Axolotl Gene Expression Data from Regenerative and Wound Healing Limb Tissues
(Nature Research, 2019)Axolotl (Ambystoma mexicanum) is a urodele amphibian endowed with remarkable regenerative capacities manifested in scarless wound healing and restoration of amputated limbs, which makes it a powerful experimental model for ... -
Investigation of effects of short-term exposure to 50HZ magnetic field on central, peripheral, and autonomic nervous systems in rats
(Wiley-Blackwell, 2015)Although a large number of exposure studies have been carried out to investigate possible detrimental effects of a power-line frequency magnetic field (PF-MF; 50-60Hz) on living organisms, there is no consensus in reported ... -
Investigation of genetic variations of IL17 for vitiligo disease
(Kuwait Medical Assoc, 2019)Objective: Vitiligo is a disorder of pigmentation characterized by the presence of depigmented skin macules due to a chronic and progressive loss of melanocytes from the cutaneous epidermis. Among many different etiologic ... -
Investigation of the Effect of Teripataid on Astrocytes
(WILEY, 2022)Teriparatide is a form of parathyroid hormone which is an effective anabolic agent used in the treatment of osteoporosis -
The investigation of therapeutic potential of oxytocin and liraglutide on vincristine-induced neuropathy in rats
(Wiley, 2020)The aim of this study was to assess the therapeutic potential of oxytocin and liraglutide (LIR), a GLP-1 analogue, in a rat model of vincristine-induced neuropathy. Rats were injected with vincristine (VCR) at a dose of 4 ... -
INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS
(Süleyman Demirel Üniversitesi, 2022)Objective The usage of mesenchymal stem cells (MSC) with immunosuppressive drugs after organ transplantation is becoming remarkable in clinical applications. However, the drugs negatively affect MSCs. Ursodeoxycholic acid ... -
Investigation on flow and heat transfer of compact brazed plate heat exchanger with lung pattern
(Pergamon-Elsevier Science Ltd, 2020)This study relates to an evaluation of the thermo-hydraulic performance for a state-of-the-art compact brazer plate heat exchanger (PHE) in 3 kW for 3-plates. To improve heat transfer and pressure drop of the PHE, a lung ... -
Is losartan a promising agent for the treatment of type 1 diabetes-induced testicular germ cell apoptosis in rats?
(Springer Science and Business Media B.V., 2022)Background: Diabetes mellitus (DM) is common metabolic disease that poses a major risk to public health and fertility. Previous studies indicate that DM may cause male infertility by triggering oxidative stress and germ ... -
İnsan Endometriyum Epitel Hücrelerinde Farklı Kontrollü Ovaryan Hipersitümulasyonu Protokollerinin Eksozom Belirteci CD63 Üzerine Etkisi
(Celal Bayar Üniversitesi, 2022)Giriş ve Amaç: Eksozomlar; protein, mRNA ve miRNA’ları taşıyan ve hedefledikleri hücrelerde/dokularda fonksiyonel değişikliklere neden olan kargo sistemleridir. CD63, eksozomların tanımlanması ve izolasyonu için anahtar ... -
Kanser Tanısı Alan Çocuk/Ergenlerin Onay Sürecine ve Tedaviye Katılımlarının Değerlendirilmesi
(2016)Kanser gibi yaşamı tehdit eden hastalık durumunda hekimler arasında tıbbi gerçeğin hastaya söylenmesi eğilimi her ülkenin kendi ahlaksal, sosyal ve kültürel yapısına göre farklılık gösterebildiği gibi, ülkelerin sağlık ... -
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease
(Journal of Chemical Neuroanatomy, 2023)Background: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that primarily affects the motor system. Although there are several treatments available to alleviate PD symptoms, there is ... -
Leptin Accelerates Endothelial Wound Healing: Role of Endothelial Nitric Oxide Synthase Expression
(Turkish Society of Cardiology, 2022)Background: The endothelium is crucial for the control of vascular homeostasis and plays a role in angiogenesis. Leptin, a protein released mainly by adipose tissue, plays a key role in the regulation of energy balance and ... -
Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress
(Taylor and Francis Ltd., 2021)The aim of the present study was to investigate the therapeutic and protective effects of linalool against doxorubicin (DOX)-induced kidney injury. Forty-eight Wistar rats were divided into 8 groups as follows; Control, ... -
Long-Term Prophylactic Transcranial Direct Current Stimulation Ameliorates Allodynia and Improves Clinical Outcomes in Individuals With Migraine
(ELSEVIER, 2023)Objectives: Migraine is a common and substantially debilitating disorder that may associate with allodynia, a marker of central sensitization in the pain circuits. Several unmet needs, like limited adherence to drugs due ... -
Losartan ameliorates ovarian ischaemia/reperfusion injury in rats: an experimental study
(Taylor & Francis Inc, 2020)This study aimed to investigate the protective and antioxidant role of losartan in ovarian ischaemia and ischaemia/reperfusion injury in an experimental ovarian torsion model. Thirty adult female rats were used. Rats were ...