Yazar "0000-0003-2274-9752" için Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
-
Hydroquinidine displays a significant anticarcinogenic activity in breast and ovarian cancer cells via inhibiting cell-cycle and stimulating apoptosis
Yavuz, Mervenur; Demircan, Turan; Şahin, Betül; Baykal, Ahmet Tarık (TUBITAK, 2023)Breast and ovarian cancers are women’s most commonly diagnosed cancers. Seeking an efficient anticarcinogenic compound is still a top priority regarding the aggressiveness of these cancers and the limited benefit of current ... -
In vitro anti-carcinogenic effect of andarine as a selective androgen receptor modulator on MIA-PaCa-2 cells by decreased proliferation and cell-cycle arrest at G0/G1 phase
Bölük, Aydın; Yavuz, Mervenur; Demircan, Turan; Takanlou, Maryam Sabour; Avcı, Çığır Biray (Elsevier Ltd, 2023)Pancreatic cancer (PC) continues to be devastating due to its highly malignant nature and poor prognosis. The limited benefits of the chemotherapeutic drugs and increasing resistance pose a critical challenge to overcome ... -
A potent ion channel blocker, hydroquinidine, exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells
Yavuz, Mervenur; Demircan, Turan (Springer Science and Business Media B.V., 2023)Background: Despite recent advances in drug discovery, cancer is still one of the most lethal health problems worldwide. In most cases, standard therapy methods and multi-modal treatments fail, and new therapeutic approaches ...