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Toplam kayıt 34, listelenen: 21-30
Neuroprotection by melatonin against acrylamide-induced brain damage in pinealectomized rats
(Elsevier B.V., 2022)
The current study aimed to evaluate the neuroprotective effect of exogenous melatonin against acrylamide (ACR)-induced oxidative stress and inflammatory and apoptotic responses in the brain tissues in pinealectomized rats ...
Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease
(PMC, 2022)
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE) are involved in modulating cholinergic signaling, but their roles in Alzheimer's and Parkinson's diseases (AD and PD) remain unclear. We identified a higher ...
Phytochemistry, Biological Activity and Toxicity of Botanical Dietary Supplement: KL21
(Celal Bayar Üniversitesi, 2022)
The use of nutritional supplements has grown conspicuously over the last decades. The present study aimed to design, develop, and optimize the toxicological and biological procedures to perform the quantitative determination ...
Evidence for modulation of planning and working memory capacities by transcranial direct current stimulation in a sample of adults with attention deficit hyperactivity disorder
(Elsevier Ireland Ltd, 2022)
Background and Objective: Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that affects up to 2.8% of the adult population. Albeit pharmacological and behavioral therapies alleviate ...
Changes in Tears Monocyte Chemoattractant Protein-1 Level after External Dacryocystorhinostomy in Primary Acquired Nasolacrimal Duct Obstruction
(Lippincott Williams and Wilkins, 2022)
Background: The authors aimed to define tears monocyte chemoattractant protein-1 (MCP-1) changes after external dacryocystorhinostomy surgery. Materials and Methods: Tears samples were collected with a Schirmer strip and ...
Leptin Accelerates Endothelial Wound Healing: Role of Endothelial Nitric Oxide Synthase Expression
(Turkish Society of Cardiology, 2022)
Background: The endothelium is crucial for the control of vascular homeostasis and plays a role in angiogenesis. Leptin, a protein released mainly by adipose tissue, plays a key role in the regulation of energy balance and ...
INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS
(Süleyman Demirel Üniversitesi, 2022)
Objective The usage of mesenchymal stem cells (MSC) with immunosuppressive drugs after organ transplantation is becoming remarkable in clinical applications. However, the drugs negatively affect MSCs. Ursodeoxycholic acid ...
İnsan Endometriyum Epitel Hücrelerinde Farklı Kontrollü Ovaryan Hipersitümulasyonu Protokollerinin Eksozom Belirteci CD63 Üzerine Etkisi
(Celal Bayar Üniversitesi, 2022)
Giriş ve Amaç: Eksozomlar; protein, mRNA ve miRNA’ları taşıyan ve hedefledikleri hücrelerde/dokularda fonksiyonel değişikliklere neden olan kargo sistemleridir. CD63, eksozomların tanımlanması ve izolasyonu için anahtar ...
Mixed lineage kinase domain-like pseudokinase: Conventional (necroptosis) and unconventional (necroptosis-independent) functions and features
(Academic Press Inc., 2022)
Mixed lineage kinase domain-like pseudokinase (MLKL) is the terminal and indispensable mediator of necroptosis. Necroptosis, also known as programmed cell necrosis, is a caspase-independent cell death mechanism involved ...
Is losartan a promising agent for the treatment of type 1 diabetes-induced testicular germ cell apoptosis in rats?
(Springer Science and Business Media B.V., 2022)
Background: Diabetes mellitus (DM) is common metabolic disease that poses a major risk to public health and fertility. Previous studies indicate that DM may cause male infertility by triggering oxidative stress and germ ...