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Toplam kayıt 96, listelenen: 81-90
Identifying Potential miRNA Biomarkers for Gastric Cancer Diagnosis Using Machine Learning Variable Selection Approach
(Frontiers Media S.A., 2022)
Aim: This study aimed to accurately identification of potential miRNAs for gastric cancer (GC) diagnosis at the early stages of the disease. Methods: We used GSE106817 data with 2,566 miRNAs to train the machine learning ...
Neuroprotection by melatonin against acrylamide-induced brain damage in pinealectomized rats
(Elsevier B.V., 2022)
The current study aimed to evaluate the neuroprotective effect of exogenous melatonin against acrylamide (ACR)-induced oxidative stress and inflammatory and apoptotic responses in the brain tissues in pinealectomized rats ...
Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease
(PMC, 2022)
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE) are involved in modulating cholinergic signaling, but their roles in Alzheimer's and Parkinson's diseases (AD and PD) remain unclear. We identified a higher ...
Phytochemistry, Biological Activity and Toxicity of Botanical Dietary Supplement: KL21
(Celal Bayar Üniversitesi, 2022)
The use of nutritional supplements has grown conspicuously over the last decades. The present study aimed to design, develop, and optimize the toxicological and biological procedures to perform the quantitative determination ...
INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS
(Süleyman Demirel Üniversitesi, 2022)
Objective The usage of mesenchymal stem cells (MSC) with immunosuppressive drugs after organ transplantation is becoming remarkable in clinical applications. However, the drugs negatively affect MSCs. Ursodeoxycholic acid ...
İnsan Endometriyum Epitel Hücrelerinde Farklı Kontrollü Ovaryan Hipersitümulasyonu Protokollerinin Eksozom Belirteci CD63 Üzerine Etkisi
(Celal Bayar Üniversitesi, 2022)
Giriş ve Amaç: Eksozomlar; protein, mRNA ve miRNA’ları taşıyan ve hedefledikleri hücrelerde/dokularda fonksiyonel değişikliklere neden olan kargo sistemleridir. CD63, eksozomların tanımlanması ve izolasyonu için anahtar ...
Is losartan a promising agent for the treatment of type 1 diabetes-induced testicular germ cell apoptosis in rats?
(Springer Science and Business Media B.V., 2022)
Background: Diabetes mellitus (DM) is common metabolic disease that poses a major risk to public health and fertility. Previous studies indicate that DM may cause male infertility by triggering oxidative stress and germ ...
Novel activity of human BChE: Lipid hydrolysis
(ELSEVIER FRANCE, 2023)
Acetylcholinesterase and butyrylcholinesterase (BChE) typically hydrolyze the neurotransmitter acetylcholine. The multifunctional enzyme BChE is associated with lipid metabolism through an undefined mechanism. Based on ...
Relationship between cognitive functions, levels of NR2A and NR2B subunits of hippocampal NMDA receptors, serum TGF-β1 level, and oxidative stress in rats fed a high-fat diet
(Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Science, 2022)
Although, excessive caloric intake is known to cause cognitive impairment, the possible mechanism behind this phenomenon is still unknown. Several studies have reported subunit composition changes in hippocampal ...
A new strategy to achieve high antimicrobial activity: green synthesised silver nanoparticle formulations with Galium aparine and Helichrysum arenarium
(SCIENDO, 2023)
Silver nanoparticles (AgNPs), which have recently gained attention due to their antimicrobial activity, can also be produced by green synthesis. The aims of this study were to (i) characterise green synthesized AgNPs using ...