Yazar "Kara, Murat" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
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MTUS1 tumor suppressor and its miRNA regulators in breast cancer
Kara, Murat; Kaplan, Mehmet; Bozgeyik, İbrahim; Özcan, Önder; Çelik, Özgür İlhan; Bozgeyik, Esra; Yumrutaş, Önder (Elsevier Science Bv, 2016)Breast cancer is major public health problem predominantly effects female population. Current therapeutic approaches to deal with breast cancer are still lack of effectiveness. Thus, identifying/developing novel strategies ... -
Paraoxonase-1 gene in patients with chronic obstructive pulmonary disease investigation Q192R and L55M polymorphisms
Gurbuz, Sukru; Yildiz, Mustafa; Kara, Murat; Kargun, Kursat; Gurger, Mehtap; Atescelik, Metin; Alatas, Omer Dogan (Zhejiang Univ Sch Medicine, 2015)BACKGROUND: The effect of increased oxidative stress on the development of chronic obstructive pulmonary disease (COPD) is well known. One of the antioxidative systems against oxidative stress in human body is paraoxonase ... -
Polymorphisms in ADAMTS4 and ADAMTS5 are not linked to susceptibility to knee osteoarthritis in the Turkish population
Canbek, Umut; İmerci, Ahmet; Kara, Murat; Akgün, Ulaş; Canbek, T. D.; Aydoğan, Nevres Hürriyet (Funpec-Editora, 2016)Considering the functions of aggrecanase-1 (ADAMTS4) and -2 (ADAMTS5), which are thought to be the two major enzymes responsible for the destruction of aggrecans in arthritic diseases, we investigated whether important ... -
Protective effects of vitamin C and vitamin E against hysterosalpingography-induced epithelial degeneration and proliferation in rat endometrium
Pala, Şehmus; Atılgan, Remzi; Kuloğlu, Tuncay; Kara, Murat; Başpınar, Melike; Can, Behzat; Artaş, Gökhan (Dove Medical Press Ltd, 2016)Aim: The aim of this study was to examine the protective effects of vitamin C (VC) and vitamin E (VE) against hysterosalpingography (HSG)-induced epithelial degeneration and proliferation in rat endometrium. Materials and ... -
The relationship between gestational diabetes mellitus and selenoprotein-P plasma 1 (SEPP1) gene polymorphisms
Akbaba, Gülhan; Akbaba, Eren; Şahin, Cem; Kara, Murat (Taylor & Francis Ltd, 2018)Our aim is to demonstrate any correlation between gestational diabetes mellitus (GDM) and polymorphism of the selenoprotein P (SEPP1) gene encoding the SEPP1 protein, having a role in the insulin resistance in GDM. Forty ... -
The rs3768777-G allele of ITGAV gene is associated with rheumatoid arthritis
Koca, Suleyman Serdar; Kara, Murat; Ozgen, Metin; Dagli, Mustafa Necati; Gozel, Nevzat; Yolbas, Servet; Isik, Ahmet (Springer Heidelberg, 2014)Integrin alpha v beta 3 (vitronectin receptor) plays a prominent role in angiogenesis, a key pathogenic feature of rheumatoid arthritis (RA). Moreover, integrin alpha(V) (ITGAV) subunit gene has been associated with a ... -
Serum adropin level and ENHO gene expression in systemic sclerosis
Yolbaş, Servet; Kara, Murat; Yılmaz, Musa; Aydın, Süleyman; Koca, Süleyman Serdar (Springer London Ltd, 2016)Adropin, a secreted protein, is encoded by the energy homeostasis associated (ENHO) gene. It has been implicated in the several physiological and pathological processes such as angiogenesis and apoptosis. Therefore, the ... -
Serum IL-33 level and IL-33 gene polymorphisms in Behcet's disease
Koca, Süleyman Serdar; Kara, Murat; Deniz, Fırat; Özgen, Metin; Demir, Caner Feyzi; İlhan, Nevin; Isık, Ahmet (Springer Heidelberg, 2015)Beh double dagger et's disease (BD) is a chronic inflammatory disease. Increased productions of cytokines including interleukin (IL)-1 beta and IL-18 are documented, and IL-1 alpha and beta gene polymorphisms are associated ... -
Sirtuin gene polymorphisms are associated with chronic obstructive pulmonary disease in patients in Mugla province
Kalemci, Serdar; Edgunlu, Tuba Gokdogan; Kara, Murat; Turkcu, Ummuhani Ozel; Cetin, Esin Sakalli; Zeybek, Arife (Termedia Publishing House Ltd, 2014)Introduction: Chronic obstructive pulmonary disease (COPD) is an irreversible progressive chronic inflammatory disease that causes shortness of breath in consequence of a decrease in pulmonary functions. The pulmonary ... -
Upregulation of SIRT1 gene in gastric adenocarcinoma
Özcan, Önder; Belli, Ahmet Korkut; Çetin, Esin Sakallı; Kara, Murat; Çelik, Özgur İlhan; Kaplan, Mehmet; Polat, Murat (Aves, 2019)Background/Aims: SIRT1 gene overexpression is reportedly associated with cancer development, via the triggering of DNA repair impairment, and cell proliferation. The study aimed to investigate SIRT1 expression in patients ...