Yazar "MÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
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Prodynorphin (PDYN) gene polymorphisms in Turkish patients with methamphetamine use disorder, changes in PDYN serum levels in withdrawal and the relationship between PDYN, temperament and depression
Senormanci, Guliz; Turan, Cetin; Celik, Sevim Karakas; Celik, Aycan; Gökdoğan Edgünlü, Tuba; Akbaş, Dilek; Senormanci, Omer (Routledge Journals, Taylor & Francis Ltd, 2020)Aim of the study is to compare prodynorphin (PDYN) rs1997794, rs1022563, rs6045819, rs2235749 polymorphisms in individuals with methamphetamine use disorder (MD) to that of healthy controls (HC), and to investigate the ... -
The protective and therapeutic effects of linalool against doxorubicin-induced cardiotoxicity in Wistar albino rats
Öner, Z.; Altinöz, E.; Elbe, Hülya; Ekinci, N. (Sage Publications Ltd, 2019)The aim of the present study was to determine the protective and therapeutic effects of linalool (LIN) against doxorubicin (DOX)-induced cardiotoxicity in rats histologically and biochemically. In experiments, 64 male ... -
Protective effect of oxytocin on a methotrexate-induced ovarian toxicity model
Hortu, İsmet; Özçeltik, Gökay; Ergenoğlu, Ahmet Mete; Yiğittürk, Gürkan; Atasoy, Özüm; Erbaş, Oytun (Springer Heidelberg, 2020)Purpose Although cancer predominantly affects people at older ages, a substantial number of patients, like breast cancer patients, are diagnosed before they have completed their families or even before giving birth. ... -
The protective effects of caffeic acid phenethyl ester against toluene-induced nephrotoxicity in rats
Meydan, Sedat; Nacar, Ahmet; Öztürk, Hasan Oktay; Taş, Ufuk; Köse, Evren; Zararsız, İsmail; Kuş, İlter; Yılmaz, Nigar (Sage Publications Inc, 2016)Caffeic acid phenethyl ester (CAPE) has antioxidant and anti-inflammatory properties. The aim of this study is to examine the negative effects of toluene on kidney tissues and functions and to investigate the protective ... -
Protective effects of quercetin against testis damage caused by cisplatin
Bostancıeri, Nuray; Taşlıdere, Aslı; Elbe, Hülya; Taşlıdere, Elif (Taylor and Francis Ltd., 2021)We investigated the effects of quercetin on cisplatin induced testicular toxicity using histopathological, immunohistochemical and biochemical methods. We used four groups of Wistar albino male: control, quercetin, cisplatin, ... -
Protective effects of vitamin C and vitamin E against hysterosalpingography-induced epithelial degeneration and proliferation in rat endometrium
Pala, Şehmus; Atılgan, Remzi; Kuloğlu, Tuncay; Kara, Murat; Başpınar, Melike; Can, Behzat; Artaş, Gökhan (Dove Medical Press Ltd, 2016)Aim: The aim of this study was to examine the protective effects of vitamin C (VC) and vitamin E (VE) against hysterosalpingography (HSG)-induced epithelial degeneration and proliferation in rat endometrium. Materials and ... -
Protein Oxidation Levels After Different Corneal Collagen Cross-Linking Methods
Türkcü, ÜmmÜhani Özel; Yüksel, Nilay; Novruzlu, Şahin; Yalınbaş, Duygu; Bilgihan, Ayse; Bilgihan, Kamil (Lippincott Williams & Wilkins, 2016)Purpose: To evaluate advanced oxidation protein products (AOPP) levels, superoxide dismutase (SOD) enzyme activity, and total sulfhydryl (TSH) levels in rabbit corneas after different corneal collagen cross-linking (CXL) ... -
Quercetin protection against ciprofloxacin induced liver damage in rats
Taşlıdere, E.; Doğan, Z.; Elbe, Hülya; Vardı, N.; Çetin, A.; Türköz, Y. (Taylor & Francis Ltd, 2016)Ciprofloxacin is a common, broad spectrum antibacterial agent; however, evidence is accumulating that ciprofloxacin may cause liver damage. Quercetin is a free radical scavenger and antioxidant. We investigated histological ... -
The relationship between hypertension and plasma allantoin, uric acid, xanthine oxidase activity and nitrite, and their predictive capacity in severe preeclampsia
Elmas, Oğuz; Elmas, Onur; Alıcıgüzel, Yakup; Şimsek, Tayyup (Taylor & Francis Inc, 2016)It is controversial that uric acid (UA) levels are related to the severity of hypertension in preeclampsia (PE). Our aim in this study was to determine whether UA, xanthine oxidase activity (XOA), allantoin and nitrite ... -
The relationship between phthalates and obesity: serum and urine concentrations of phthalates
Oktar, Süleyman; Sungur, Sana; Okur, Ramazan; Yılmaz, Nigar; Üstün, Ihsan; Gökce, Cumali (Edizioni Minerva Medica, 2017)BACKGROUND: A limited number of human and animal studies suggest that a relationship exists between phthalates and obesity, although this is not supported by all research. The purpose of this study was to investigate the ... -
Reply to Letter to the Editor: "Fragmented QRS Pattern in Patients with COVID-19: Further Insights into Its Temporal and Mechanistic Features"
Özdemir, İbrahim Halil; Özlek, Bülent; Özlek, Eda (Kare Publishing, 2022)We have recently read with great interest the article entitled Fragmented QRS pattern in patients with COVID-19: -
The Restorative Effect of Gallic Acid on the Experimental Sciatic Nerve Damage Model
Gürkan, Gökhan; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun (Korean Neurosurgical Society, 2021)Objective: Peripheral nerve injuries occur mostly as a result of mechanical trauma. Due to the microvascular deterioration in peripheral nerve damage, it becomes challenging to remove free oxygen radicals. Gallic acid is ... -
Resveratrol reduces light and electron microscopic changes in acetaminophen-induced hepatotoxicity in rats: Role of iNOS expression
Elbe, Hülya; Gül, Mehmet; Çetin, Aslı; Taşlıdere, Elif; Özyalın, Fatma; Türköz, Yusuf; Otlu, Ali (Taylor & Francis Inc, 2018)Introduction: Hepatotoxicity is amajor complication of acetaminophen (APAP), a widely used analgesic and antipyretic drug. Resveratrol (RSV) is a naturally occurring diphenol and it has anticancer, antioxidant, and ... -
The Role of Ankaferd Blood Stopper and Oxytocin as Potential Therapeutic Agents in Endometriosis: A Rat Model
Hortu, Ismet; Ozceltik, Gokay; Karadadas, Elif; Erbas, Oytun; Yiğittürk, Gürkan; Ulukus, Murat (Springer, 2020)To evaluate the potential effect of Ankaferd Blood Stopper (ABS) and oxytocin (OT) in an experimental endometriosis model, 18 female Sprague Dawley rats were used in this study. The animals were divided randomly into three ... -
The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea
Saruhan, Ercan; Sertoğlu, Erdim; Ünal, Yasemin; Bek, Semai; Kutlu, Gülnihal (Springer Heidelberg, 2020)Purpose Obstructive sleep apnea (OSA) is a disorder characterized by recurrent episodes of obstruction of the upper respiratory tract during sleep often accompanied by oxygen desaturations. Antioxidant defense mechanisms ... -
A selective androgen receptor modulator, S4, displays robust anti-cancer activity on hepatocellular cancer cells by negatively regulating PI3K/AKT/mTOR signalling pathway
Yavuz, Mervenur; Takanlou, Leila Sabour; Avcı, Çığır Biray; Demircan, Turan (Elsevier B.V., 2023)Hepatocellular carcinoma (HCC) is a major global health problem that often correlates with poor prognosis. Due to the insufficient therapy options with limited benefits, it is crucial to identify new therapeutic approaches ... -
Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel
Çetin, Esin Sakallı; Nazıroğlu, Mustafa; Çiğ, Bilal; Övey, İshak Suat; Koşar, Pınar Aslan (Taylor & Francis Ltd, 2017)Background: In breast cancers, calcium signaling is a main cause of proliferation and apoptosis of breast cancer cells. Although previous studies have implicated the transient receptor potential vanilloid 1 (TRPV1) cation ... -
Serum and Aqueous Humor Levels of Fetuin-A in Pseudoexfoliation Syndrome
Yüksel, Nilay; Takmaz, Tamer; Özel Türkcü, Ümmühani; Ergin, Merve; Altınkaynak, Hasan; Bilgihan, Ayşe (Taylor & Francis Inc, 2017)Purpose: To evaluate serum and aqueous humor levels of fetuin-A in patients with pseudoexfoliation syndrome (PEXS) in comparison with those of age- and sex-matched healthy subjects.Materials and Methods: This prospective ... -
A surgical and anatomo-histological study on Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA)
Çelik, Servet; Makay, Özer; Yörük, Mustafa Deniz; Koçer, İlke Bayzıt; Özdemir, Murat; Kılıç, Kubilay Doğan; Dionigi, Gianlorenzo (Springer, 2020)Background The number of TOETVA surgeries has increased worldwide but the anatomical passage of trocars is not clearly defined. We aimed to define detailed surgical anatomical passage of the trocars in cadavers. The incisions ... -
Therapeutic Effects of Liraglutide, Oxytocin and Granulocyte Colony-Stimulating Factor in Doxorubicin-Induced Cardiomyopathy Model: An Experimental Animal Study
Taşkıran, Emin; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun (Humana Press Inc, 2019)Doxorubicin-induced (DXR) cardiomyopathy is a serious health issue in oncology patients. Effective treatment of this clinical situation still remains to be discovered. In this experimental animal study, we aimed to define ...