Yazar "0000-0002-9300-9324" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
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Exploration of Potential miRNA Biomarkers and Prediction for Ovarian Cancer Using Artificial Intelligence
Hamidi, Farzaneh; Gilani, Neda; Belaghi, Reza Arabi; Sarbakhsh, Parvin; Edgünlü, Tuba; Santaguida, Pasqualina (MedGen, 2021)Ovarian cancer is the second most dangerous gynecologic cancer with a high mortality rate. The classification of gene expression data from high-dimensional and small-sample gene expression data is a challenging task. The ... -
Identifying Potential miRNA Biomarkers for Gastric Cancer Diagnosis Using Machine Learning Variable Selection Approach
Gialini, Neda; Belaghi, Reza Arabi; Aftabi, Younes; Faramarzi, Elnaz; Edgünlü, Tuba (Frontiers Media S.A., 2022)Aim: This study aimed to accurately identification of potential miRNAs for gastric cancer (GC) diagnosis at the early stages of the disease. Methods: We used GSE106817 data with 2,566 miRNAs to train the machine learning ... -
In Vitro Effects of Propofol on Cytotoxic, Apoptotic and PI3K-Akt Signaling Pathway Genes on Brain Cancer Cells
Gökdoğan Edgünlü, Tuba; Avcı, Cigir Biray; Özateş, Neslihan Pınar; Göker Bağca, Bakiye; Karakaş Çelik, Sevim; Bölük, Aydın; Uğur, Bakiye (Bentham Science, 2021)Aim: It was aimed to determine the cytotoxic and apoptotic effect of propofol on glioma cells. Background: Propofol [2,6-diisopropylphenol] is a commonly used intravenous anesthetic. Propofol is known to have a mechanism ... -
miR-181a-5p is a potential candidate epigenetic biomarker in multiple sclerosis
Edgünlü, Tuba; Görücü Yılmaz, Şenay; Emre, Ufuk; Taşdelen, Bahar; Kuru, Oktay; Kutlu, Gülnihal; Erdal, Mehmet Emin (NLM (Medline), 2022)Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and axonal degeneration. Abnormal expression of microRNAs (miRNAs) plays an important role in MS ... -
The role of adropin, salusin-α, netrin-1, and nesfatin-1 in endometriosis and their association with insulin resistance
Akbaba, Eren; Sezgin, Burak; Edgünlü, Tuba (GALENOS YAYINCILIK, 2021)Objective: The pathogenesis of endometriosis has not been clearly explained. Inflammatory factors of ectopic implantation and the growth of ectopic endometrial cells have been subjects of major interest. The number of ... -
Vesicle trafficking with snares: a perspective for autism
Özdemir, Çilem; Şahin, Nilfer; Edgünlü, Tuba (Springer Science and Business Media B.V., 2022)Vesicle-mediated membrane traffic is the mechanism fundamental to many biological events, especially the release of neurotransmitters. The main proteins of the mechanism that mediates membrane fusion in vesicle-mediated ...