• Natural Product r esearch Alkaloid contents and biological activities of Genista lydia Boiss. 

  Sabudak, Temine; Argon, Merve; Çakır, Cansel; c (Taylor & Francis, 2026)

  This study aimed to investigate the biological activities and alkaloid composition of Genista lydia Boiss. (syn. Genista januensis subsp. lydia) growing in the Trakya Region. The plant material was sequentially extracted ...

• Sustainable Bioactive Hydrogels Engineered with Liquidambar orientalis Extracts: pH-Dependent Release Behavior and Wound Healing Potential 

  Taş Küçükaydın, Meltem; Duru, Mehmet Emin; Demiray, Aydın; Küçükadın, Selçuk; Ceylan, Özgür (WILEY, 2026)

  Bioactive hydrogel films were developed by incorporating Liquidambar orientalis leaf extract (LOLE) and resin extract (LORE) into PVA/starch, PVA/chitosan, chitosan/gelatin, and chitosan matrices. HPLC-DAD identified ...

• A Hybrid Nanomaterial-Based Electrochemical Sensor for Melatonin Measurement in Human Saliva: A Diagnostic Tool for Anxiety Disorder 

  Özyurt, Vasfiye Hazal; Çaylayık, Nil Su; Çitil, Burak Ekrem; Türkiş, Fulden Cantaş; Anık, Ülkü (WILEY, 2026)

  Since the diagnosis of anxiety disorder is primarily based on questionnaires, accurate identification of the disorder can be challenging. Melatonin has been identified as a potential biomarker for the detection of anxiety ...

• Copper based metal organic framework decorated with gold nanoparticles as a new electrochemical sensor material for the detection of L-Cysteine in milk samples 

  Perk, Benay; Tepeli-Büyüksünetci, Yudum; Anık, Ülkü (Springer, 2023)

  A facile electrochemical sensor based on carbon felt electrode (CFE) modified with gold nanoparticles decorated copper based metal organic framework (AuNPs@Cu-MOF) was achieved for the electrochemical sensing of L-Cysteine ...

• Adsorptive Removal of Oxytetracycline Using Polymer Coated Magnetic Nanoparticular Activated Carbon: Synthesis, Characterization and Adsorption Isotherms and Kinetics Studies 

  Uğurlu, Mehmet; Osman, Hüseyn; Vaizoğullar, Ali İmran (Iranian Institute of Research and Development in Chemical Industries, 2023)

  In the presented study, the removal of oxytetracycline (OTC) from aqueous solution by adsorption was investigated onto Active Carbon (AC), Magnetic activated carbon (MagAC), Styrene-Butadiene-Styrene Magnetic Activated ...

• Synthesis, Structural Investigations, DNA/BSA Interactions, Molecular Docking Studies, and Anticancer Activity of a New 1,4-Disubstituted 1,2,3-Triazole Derivative 

  Göktürk, Tolga; Sakallı Çetin, Esin; Hökelek, Tuncer; Pekel, Hanife; Şensoy, Özge; Aksu, Ebru Nur (American Chemical Society, 2023)

  We report herein a new 1,2,3-triazole derivative, namely, 4-((1-(3,4-dichlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2-hydroxybenzaldehyde, which was synthesized by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). ...

• Assessing the Acute Toxicological Effects of Annona muricata Leaf Ethanol Extract on Rats: Biochemical, Histopathological, and Metabolomics Analyses 

  Zubaidi, Siti Norliyana; Qadi, Wasim S. M.; Maarof, Syahida; Hellal, Khaoula (MDPI, 2023)

  Annona muricata is a common plant used in Africa and South America to manage various types of disease. However, there is insufficient toxicological information or published standard available regarding repeated dose animal ...

• Photodynamic Anti-Inflammatory Activity of Porphyrin Derivative on In-Vitro Activated Macrophages 

  Haklı, Özgül; Ocakoğlu, Kasım (SPRINGER, 2023)

  Porphyrin derivatives have been known for their photodynamic therapy (PDT) application potential. In the present work, we have studied an asymmetric tetraphenyl substituted porphyrin derivative synthesized previously. ...

• Design, in Silico Studies and Biological Evaluation of New Chiral Thiourea and 1,3-Thiazolidine-4,5-dione Derivatives 

  Evyapan, Samet; Oruç-Emre, Emine Elçin; Sıcak, Yusuf; Karaküçük-İyidoğan, Ayşegül; Öztürk, Mehmet; Yılmaz Tatar, Gizem (John Wiley and Sons Inc, 2023)

  In this study, new chiral thiourea and 1,3-thiazolidine-4,5-dione derivatives were synthesized, it was aimed to evaluate the various biological activities and molecular docking of these compounds. Firstly, the new thioureas ...

• Bioactive molecules from Algerian propolis with therapeutic potential against the oral pathogen Enterococcus faecalis and Chromobacterium violaceum CV026 

  Mokrani, Meryem; Zellagui, Amar; Hadjab, Widad; Öztürk, Mehmet; Ceylen, Özgür; Bensouici, Chawki (SciCell s.r.o., 2023)

  This research aims to analyse the richness of propolis ethanolic extract from Kherrata (EEPKh) in phenolic and flavonoid compounds and its antioxidant effects using different methods. Further investigations were conducted ...

• Fabrication of metal-organic framework based electrochemical Leishmania immunosensor 

  Tepeli-Büyüksünetci, Yudum; Perk, Benay; Bouzaien, Sana Bachraoui; Diouani, Mohamed F.; Anık, Ülkü (ELSEVIER, 2023)

  Leishmaniasis is a disease with a high impact on public health in many countries. In this study, an electro-chemical immunosensor for Leishmania major surface protease (Gp63) antibody detection was developed using copper ...

• Synthesis, spectroscopic characterization, crystal structure and biological properties of novel co-crystal copper(II) complex containing dioxime ligand 

  Gökçe Topkaya, Cansu; Sakallı Çetin, Esin; Göktürk, Tolga; Kıncal, Sultan; Hökelek, Tuncer; Güp, Ramazan (Elsevier B.V., 2023)

  The title compound, co-crystal [(aqua) (1E,1′E,2E,2′E)-2,2′-(propane-1,3-diylbis(azaneylylidene)) bis(2-phenylacetaldehyde)dioximato] copper(II)chlorate, [Cu(HL1)ClO4]3, was synthesized from 1,3-diaminopropane and ...

• Synthesis, Crystal Structure, Hirshfeld Surface Analysis, DNA/BSA Interaction and Molecular Docking Studies of 2-(6-(4-chlorophenyl)-1,2,4-triazin-3-yl)quinoline 

  Göktürk, Tolga; Zengin, Talip; Hökelek, Tuncer; Gökçe Topkaya, Cansu; Güp, Ramazan (Elsevier B.V., 2023)

  We reported herein a new 1,2,4-triazine derivative, 2-(6-(4-chlorophenyl)-1,2,4-triazin-3-yl)quinoline, synthesized by cyclization of p‑chloro isonitrosophenylhydrazine with 2-quinolinecarboxaldehyde. Its structure was ...

• Electrospun modified PAN-porphyrin nanofiber electrode for caffeine detection 

  Güzel, Umut; Tepeli-Büyüksünetci, Yudum; Haklı, Özgül; Oylumluoğlu, Görkem; Anık, Ülkü (Elsevier Ltd, 2023)

  In this work, caffeine sensitive electrospun polyacrylonitrile-(5,10,15,20-tetra(4-tert butylphenyl)-porphyrin)/carbon felt electrode (PAN-Por/CFE) nanofiber (NF) electrochemical sensor was fabricated. In this manner, this ...

• Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation 

  Altuntaş, Mehmet; Altuntaş, Derya Bal; Aslan, Sema; Yılmaz, Ersin; Nalbant, Ercan (American Chemical Society, 2023)

  Core-shell quantum dot ZnS/CdSe screen-printed electrodes were used to electrochemically measure human blood plasma levels of exogenous adrenaline administered to cardiac arrest patients. The electrochemical behavior of ...

• HPLC-DAD Analysis and Versatile Bioactivities of Turkish Sunflower Honeys Using Chemometric Approaches 

  Duru, Mehmet Emin; Eroğlu, Büşra; Tel-Çayan, Gülsen; Taş-Küçükaydın, Meltem; Küçükaydın, Selçuk; Çayan, Fatih; Ceylan, Özgür (John Wiley and Sons Inc, 2023)

  Sunflower honey (SH) is bright yellow, fragrant, pollen-flavoured, slightly herbaceous and has a unique taste. The present research aims to examine the enzyme inhibitory, antioxidant, anti-inflammatory, antimicrobial and ...

• Milk lactose removal by β-galactosidase immobilized on eggshell membrane 

  Kızıldağ, Selen; Işık, Ceyhun; Teke, Mustafa (Springer Science and Business Media Deutschland GmbH, 2023)

  Eggshell membrane (ESM) is used in immobilization studies due to its large surface area, non-toxicity and biodegradability. In this study, β-galactosidase was immobilized on ESM using the adsorption and cross-linking method. ...

• Bismuth film based electrochemical hydroxymethylfurfural sensor 

  Özyurt, Vasfiye Hazal; Avcı, Okan; Tepeli-Büyüksünetci, Yudum; Anık, Ülkü (SPRINGER, 2023)

  A simple and sensitive electrochemical sensor based on bismuth film that was coated onto a carbon paste electrode was prepared and used for hydroxymethylfurfural (HMF) detection. It was observed that bismuth film electrode ...

• Assessment of physicochemical parameters, bioactive compounds, biological activities, and nutritional value of the most two commercialized pollen types of date palm (Phoenix dactylifera L.) in Morocco 

  Salhi, Saad; Chentouf, Mouad; Harrak, Hasnaâ; Öztürk, Mehmet; Çam, Dilaycan; Çakır, Cansel (SAGE Publications Inc., 2023)

  The pollen of date palm (Phoenix dactylifera L.) is known for its nutritional value and implications as a health-promoting component. Due to its low cost, date palm pollen crushed with its spadix is more widely commercialized ...

• The antibacterial effect of bee venom on subclinical mastitis agents: an alternative for local treatment 

  Güven Gökmen, Tülin; Yazgan, Hatice; Sevin, Sedat; Turut, Nevin; Karahan, Şifa; Eşki, Funda; Kıvrak, İbrahim (Taylor and Francis Ltd., 2023)

  Subclinical mastitis is an important problem in terms of the dairy economy all over the world and due to the increasing antibiotic resistance day by day, there is a great need for new antibiotic alternatives and natural ...

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