Erişim şekli için "info:eu-repo/semantics/openAccess" Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu listeleme
Toplam kayıt 57, listelenen: 41-57
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Molecular dynamics analysis of N-acetyl-D-glucosamine against specific SARS-CoV-2’s pathogenicity factors
(Public Library of Science, 2021)The causative agent of the pandemic identified as SARS-CoV-2 leads to a severe respiratory illness similar to SARS and MERS with fever, cough, and shortness of breath symptoms and severe cases that can often be fatal. In ... -
Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements
(Sage Publications Ltd, 2020)Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-spectrum applicability to prevent dreadful diseases such as cardiovascular disease, neurodegeneration, and cancer. The reported anticancer ... -
Morphological and molecular determination of a new Viola species (Violaceae) from Turkey
(Magnolia Press, 2018)Viola denizliensis is described as a new species from South-West Anatolia. The species grows on serpentinite stony slopes in Bozdag Mountain in Denizli. It belongs to Viola sect. Alelanium and is close to V dirindiensis ... -
Muscari macrocarpum sweet ve ornithogalum alpigenum stapf. türlerinin kültürleştirme yöntemleri
(2002)Bitki türlerinin korunmasının bir yolu da onları kültüre almaktır. Nadir bulunan ve tehlike altında bulunan Muscari macrocarpum Sweet ve Ornithogalum alpigenum Stapf. türleri üzerinde yaptığımız kültürleştirme çalışmaları, ... -
Nodal tumor volume as a prognostic factor for head and neck squamous cell carcinoma: a systematic review
(FRONTIERS IN BIOSCIENCE INC, 2021)Introduction: Several studies suggest that there is an association between the metastatic nodal tumor volume and the clinical outcome in patients with solid cancers. However, despite the prognostic potential of nodal volume, ... -
p60-katanin: a novel interacting partner for p53
(Springer, 2020)Katanin, one of the best-characterized microtubule (MT) severing proteins, is composed of two subunits: catalytic p60-katanin, and regulatory p80-katanin. p60-katanin triggers MT reorganization by severing them. MT ... -
Phenolic profile, antioxidant, and antiproliferative activities of Convolvulus aucheri Choisy
(MILITARY MEDICAL ACAD-INI, 2022)Background/Aim. It is known that some members of the genus Convolvulus (C) L. are commonly used in Turkish folk medicine. These species are powerful in curing toothache and joint pains. Due to the limited information on ... -
Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions
(MDPI, 2022)Phloretin is a natural dihydrochalcone found in many fruits and vegetables, especially in apple tree leaves and the Manchurian apricots, exhibiting several therapeutic properties, such as antioxidant, antidiabetic, ... -
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
(TAYLOR & FRANCIS INC, 2022)Although the therapeutic efficacy and commercial success of monoclonal antibodies (mAbs) are tremendous, the design and discovery of new candidates remain a time and cost-intensive endeavor. In this regard, progress in the ... -
A Proteomic Approach Provides New Insights into the Control of Soil-Borne Plant Pathogens by Bacillus Species
(Public Library Science, 2013)Beneficial microorganisms (also known as biopesticides) are considered to be one of the most promising methods for more rational and safe crop management practices. We used Bacillus strains EU07, QST713 and FZB24, and ... -
Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements
(Mdpi, 2019)Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous ROS production in normal cells is controlled by the appropriate regulation between the silver lining of low and high ROS concentration ... -
Salicylidene acylhydrazides attenuate survival of SH-SY5Y neuroblastoma cells through affecting mitotic regulator Speedy/RINGO and ERK/MAPK-PI3K/AKT signaling
(Humana Press Inc, 2020)Salicylidene acylhydrazide group synthetic compounds ME0053, ME005 and ME0192 are known for their iron chelating properties and due to these properties they are primarily used for blocking the bacterial type 3 secretory ... -
The screening of Digitalis ferruginea L. subsp. ferruginea for toxic capacities, phenolic constituents, antioxidant properties, mineral elements and proximate analysis
(SOC BRASILEIRA CIENCIA TECNOLOGIA ALIMENTOS, 2021)The present study outlines the antioxidant and toxic activity, total phenol, flavonoid and tannin content of Digitalis ferruginea?s extracts in addition to evaluating its proximate parameters and mineral elements. Successive ... -
Speedy/RINGO protein interacts with ERK/MAPK and PI3K/AKT pathways in SH-SY5Y neuroblastoma cells
(Springer, 2020)Abnormal activity of ERK/MAPK and PI3K/AKT pathways is one of the most important factors for the development of many cancer types including neuroblastoma cancer. Apart from these two pathways, some cell cycle regulators ... -
Synthesis of Adenine-based Fluorescent and Naked-eye Chemosensors: Specific DNA Probes for the Detection of Bacterial Pathogens
(Slovensko Kemijsko Drustvo, 2021)A rapid and confident tool to identify and diagnose bacterial pathogens with more accuracy using DNA as fingerprints is necessary. Herein, we report a smart chemosensor having a terminal adenine sticking to the thymine of ... -
Synthesis, Structural Investigations, and In Vitro/In Silico Bioactivities of Flavonoid Substituted Biguanide: A Novel Schiff Base and Its Diorganotin (IV) Complexes
(MDPI, 2022)Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological study of quercetin is extremely difficult due to its very low solubility. However, diorganotin complexes of quercetin are more ... -
Transcriptional analyses of the effects ofCatharanthus roseusL. medicinal plant extracts on some markers related to obesity and inflammation in 3T3-L1 mouse cell lines
(Springer, 2020)Catharanthus roseusL. (C. roseus) is one of the medicinal plants used to treat diabetes. In this study, 3T3-L1 preadipocyte cell lines which are fully differentiated into adipocytes were utilized and these were treated ...