Erişim şekli için "info:eu-repo/semantics/closedAccess" Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu listeleme
Toplam kayıt 68, listelenen: 21-40
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Cytotoxic and Antioxidant Potential of Chloroform Extract of Holothuria tubulosa Gmelin, 1791
(Springer, 2022)Abstract: Natural products are promising anticancer agents and antioxidants. The present study was aimed to evaluate the cytotoxic and antioxidant potential and the contents of phenolic compounds of a chloroform extract ... -
Data mining and molecular dynamics analysis to detect HIV-1 reverse transcriptase RNase H activity inhibitor
(nstitute for Ionics, 2023)HIV-1 is a deadly virus that affects millions of people worldwide. In this study, we aimed to inhibit viral replication by targeting one of the HIV-1 proteins and identifying a new drug candidate. We used data mining and ... -
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
(Elsevier, 2021)Cancer is an anomalous growth and differentiation of cells known to be governed by oncogenic factors. Plant-based natural metabolites have been well recognized to possess chemopreventive properties. Deguelin, a natural ... -
Doxorubicin Release from Bovine Serum Albumin Microparticles
(SPRINGER, 2022)Doxorubicin (Dox) is an anthracycline antibiotic and highly potent anticancer drug. However, its utility is often limited by severe side effects such as irreversible cardiotoxicity and reversible nephrotoxicity. In recent ... -
The effects of the Rheum ribes plant extract on inflammation, extracellular matrix remodeling, and obesity suggest a therapeutic potential
(Springer Science and Business Media B.V., 2023)Background: The prevalence of obesity is increasing in the world, and the Type II diabetes associated with obesity led researchers to seek alternative methods to treat these two chronic diseases. In the case of obesity and ... -
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
(Elsevier, 2021)Oncogenic transformation has been the major cause of global mortality since decades. Despite established therapeutic regimes, majority of cancer patients either present with tumor relapse, refractory disease or therapeutic ... -
Evaluation of Multifunctional Hybrid Analogs for Stilbenes, Chalcones and Flavanones
(Bentham Science Publ Ltd, 2017)Aims: In this study, discovery of novel anticancer agents acting by more than one mechanism was aimed. Method: For this purpose, eleven previously synthesized simple-stilbene, chalcone, flavanone derivatives and 31 novel ... -
Genetic diversity of the cosmopolitan long-legged fly Syntormon pallipes in Turkey
(Taylor and Francis Ltd., 2023)Syntormon pallipes is one of the cosmopolitan species in the family Dolichopodidae. It has an important role in agriculture and forest ecosystems. We studied the genetic diversity of 10 populations of this species using ... -
Genetic Structure of Mediterranean Fruit Fly (Ceratitis capitata) Populations in Turkey
(Ceska Zemedelska Univ & Praze, 2017)[No abstract available] -
Geographical distribution and frequencies of organophosphate-resistant Ace alleles and morphometric variations in olive fruit fly populations
(John Wiley & Sons Ltd, 2015)BACKGROUNDIn the Mediterranean basin, organophosphate (OP) insecticides have been used intensively to control olive fly populations. Acetylcholinesterase (Ace) is the molecular target of OP insecticides, and three ... -
Geographical Distribution And Frequencies Of Organophosphate-Resistant Ace Alleles In Olive Fruit Fly Populations
(Ceska Zemedelska Univ & Praze, 2017)[No abstract available] -
Host-Induced Gene Silencing: Approaches in Plant Disease Management
(Springer International Publishing, 2023)Crops exposed to the damage of various biotic and abiotic sources result in reduced yields and cause economic losses. There are prominent strategies such as breeding for improved resistance, the application of pesticides, ... -
In vitro DNA interaction, topoisomerase I/II Inhibition and cytotoxic properties of polymeric copper(II) complex bridged with perchlorate ion containing N-4-type schiff base ligand
(Elsevier, 2022)Cu(II) complex containing p-Cl-isonitrosoacetophenone based on N 4-type Schiff base ligand was synthesized and characterized by elemental analysis, FTIR, H-1 NMR, (13) C NMR and UV-Visible. The crystal structure of the ... -
Landmark based Geometric Morphometry of Bactrocera oleae (Diptera: Tephritidae) Populations in Turkey
(Ceska Zemedelska Univ & Praze, 2017)[No abstract available] -
Lichens as a Promising Source of Unique and Functional Small Molecules for Human Health and Well-Being
(Elsevier Science Bv, 2018)Drug design and discovery processes are very important for human health because of the prevalence of many diseases for which there is no known medical cure. Much scientific effort backed by the financial support of governments ... -
Metal nanoparticles in cancer: from synthesis and metabolism to cellular interactions
(SPRINGER HEIDELBERG, 2022)Nanotechnology has encouraged new and amended materials (metal nanoparticles) for therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) are versatile nanoscale entities, widely used to ... -
A missing dilemma on nanoparticle producer microorganisms
(Springer Singapore, 2020)The development of eco-friendly biological methods in material synthesis has been reported with chemically well-defined variety of inorganic nanoparticles (NP) that are produced by using various microorganisms. In last ... -
Mitochondrial genetic variations in natural house fly (Musca domestica L.) populations from the western and southern parts of Turkey
(Taylor & Francis Ltd, 2016)The house fly Musca domestica Linnaeus (Diptera) is one of the most studied species that is globally distributed and well known to everyone. In order to ensure baseline knowledge for the genetic resources of the species, ...