Başlık için Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu listeleme
Toplam kayıt 125, listelenen: 40-59
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Data mining and molecular dynamics analysis to detect HIV-1 reverse transcriptase RNase H activity inhibitor
(nstitute for Ionics, 2023)HIV-1 is a deadly virus that affects millions of people worldwide. In this study, we aimed to inhibit viral replication by targeting one of the HIV-1 proteins and identifying a new drug candidate. We used data mining and ... -
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
(Elsevier, 2021)Cancer is an anomalous growth and differentiation of cells known to be governed by oncogenic factors. Plant-based natural metabolites have been well recognized to possess chemopreventive properties. Deguelin, a natural ... -
Design and synthesis of novel organometallic complexes using boronated phenylalanine derivatives as potential anticancer agents
(Taylor & Francis Ltd, 2019)Drug design and discovery studies are important because of the prevalence of diseases without available medical cures. New anticancer agents are particularly urgent because of the high mortality rate associated with cancer. ... -
Development of an optimum proliferation medium via the graph kernel statistical analysis method for genetically stable in vitro propagation of endemic Thymus cilicicus (Turkey)
(Department of Biology, Faculty of Science, University of Zagreb, 2021)Thymus cilicicus is an endemic Eastern Mediterranean element that has aromatic-medicinal properties. Its natural population spreads across gravelly ground and open rocky areas of South and Southwest Anatolia. The current ... -
Doxorubicin Release from Bovine Serum Albumin Microparticles
(SPRINGER, 2022)Doxorubicin (Dox) is an anthracycline antibiotic and highly potent anticancer drug. However, its utility is often limited by severe side effects such as irreversible cardiotoxicity and reversible nephrotoxicity. In recent ... -
The effect of a seed coating with Origanum vulgare essential oil on Clavibacter michiganensis subsp. michiganensis
(Czech Academy of Agricultural Sciences, 2021)The study aimed to evaluate the efficacy of a seed film coating with Origanum vulgare Linnaeus essential oil (EO) against Clavibacter michiganensis subsp. michiganensis (Cmm) on tomatoes. Tomato seeds (cv. Rio Grande) ... -
The effects of the Rheum ribes plant extract on inflammation, extracellular matrix remodeling, and obesity suggest a therapeutic potential
(Springer Science and Business Media B.V., 2023)Background: The prevalence of obesity is increasing in the world, and the Type II diabetes associated with obesity led researchers to seek alternative methods to treat these two chronic diseases. In the case of obesity and ... -
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
(Elsevier, 2021)Oncogenic transformation has been the major cause of global mortality since decades. Despite established therapeutic regimes, majority of cancer patients either present with tumor relapse, refractory disease or therapeutic ... -
Evaluation of Critical Points for Effective Cryopreservation of Four Different Citrus spp. Germplasm
(MDPI, 2022)The different pre- and post-treatments are critical in cryopreservation procedures and affect the shoot tip regrowth after freezing. In the present study, the long-term storage of four citrus cultivars [Bodrum Mandarin ... -
Evaluation of Multifunctional Hybrid Analogs for Stilbenes, Chalcones and Flavanones
(Bentham Science Publ Ltd, 2017)Aims: In this study, discovery of novel anticancer agents acting by more than one mechanism was aimed. Method: For this purpose, eleven previously synthesized simple-stilbene, chalcone, flavanone derivatives and 31 novel ... -
Extracellular microRNAs: key players to explore the outcomes of in vitro fertilization
(BioMed Central Ltd, 2021)Background: MicroRNAs (miRNAs) are small RNA molecules that modulate post-transcriptional gene regulation. They are often used as promising non-invasive biomarkers for the early diagnosis of cancer. However, their roles ... -
First Report of Bacterial Blight of Pomegranate Caused by Xanthomonas axonopodis pv. punicae in Turkey
(Amer Phytopathological Soc, 2014) -
First Report of Grey Mold Caused by Botryotinia fuckeliana on Golden Berry
(Amer Phytopathological Soc, 2016) -
Genetic differentiation of non-native populations of Gibel Carp,Carassius gibelioin Western Turkey by ISSR and SRAP markers
(Taylor & Francis Ltd, 2020)Freshwater fish are one of the most frequently translocated and introduced aquatic animal groups and exhibit higher establishment ratios than many other taxa. Introductions are usually irreversible. One of common non-native ... -
Genetic diversity of the cosmopolitan long-legged fly Syntormon pallipes in Turkey
(Taylor and Francis Ltd., 2023)Syntormon pallipes is one of the cosmopolitan species in the family Dolichopodidae. It has an important role in agriculture and forest ecosystems. We studied the genetic diversity of 10 populations of this species using ... -
The Genetic Polymorphisms and Colonization Process of Olive Fly Populations in Turkey
(Public Library Science, 2013)The olive fruit fly, Bactrocera oleae, is the most important pest of olives in olive growing regions worldwide, especially in the Mediterranean basin and North America. Despite the economic importance of the olive fly, the ... -
Genetic Structure of Mediterranean Fruit Fly (Ceratitis capitata) Populations in Turkey
(Ceska Zemedelska Univ & Praze, 2017)[No abstract available] -
Genetic structure of Mediterranean fruit fly (Diptera: Tephritidae) populations from Turkey revealed by mitochondrial DNA markers
(Indian Acad Sciences, 2019)Ceratitis capitata is one among the most destructive and economically important agricultural pests worldwide. Despite its economic significance, the population structures of this pest have remained relatively unexplored ... -
GENETIC UNIFORMITY OF A SPECIFIC REGION IN SARS-CoV-2 GENOME AND REPURPOSING OF N-ACETYL-D-GLUCOSAMINE
(PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2021)The causative agent of the viral pneumonia outbreak in the world identified as SARS-CoV-2 leads to a severe respiratory illness like SARS and MERS. The pathogen spreading has turned into a pandemic dissemination and increased ... -
GENOMIC CHARACTERIZATION AND PHYTOSTIMULATIVE EFFECT OF A NOVEL SERRATIA SPECIES
(Serbian Genetics Society, 2022)Some of non-pathogenic bacteria are effective biocontrol agents and plant growth inducers besides its degradative property on polycyclic aromatic hydrocarbons (PAH). Herein, we report a novel candidate Serratia species ...
