Başlık için Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu listeleme
Toplam kayıt 125, listelenen: 105-124
-
Phylogenetic Analysis of Olea europaea L. Cultivars Using LTRs (Long Term Repeats) Retrotransposon-based Marker Systems.
(Springer, 2016)[No abstract available] -
Polymer-mediated nanoformulations: a promising strategy for cancer immunotherapy
(Springer Science and Business Media Deutschland GmbH, 2023)Engineering polymer-based nano-systems have attracted many researchers owing to their unique qualities like shape, size, porosity, mechanical strength, biocompatibility, and biodegradability. Both natural and synthetic ... -
Potential cancer treatment effects of brusatol or eriodictyol combined with 5-fluorouracil (5-FU) in colorectal cancer cell
(SPRINGER, 2022)Colorectal cancer is among the most frequently diagnosed cancers in patients today. In the treatment of this disease, combination or multicomponent therapy has been identified as a potential method to improve patient ... -
A potential posttranscriptional regulator for p60-katanin: miR-124-3p
(John Wiley and Sons Inc, 2023)Katanin is a microtubule severing protein belonging to the ATPase family and consists of two subunits; p60-katanin synthesized by the KATNA1 gene and p80-katanin synthesized by the KATNB1 gene. Microtubule severing is one ... -
Preparation of Spherical Cellulose Nanoparticles from Recycled Waste Cotton for Anticancer Drug Delivery
(John Wiley and Sons Inc, 2021)Using natural waste resources as a starting material for the preparation of cellulose nanoparticles is a field of interest for novel pharmaceutical applications. This study aims to introduce cellulose nanoparticles for ... -
The Prevalence and Genetic Characterization of Strains of Borrelia Isolated from Ixodes Tick Vectors in Belarus (2012-2019)
(Mary Ann Liebert, 2021)Borrelia burgdorferi sensu lato (s.l.) is the most common pathogen of medical significance transmitted by ticks of the family Ixodidae in Belarus. Human infection with B. burgdorferi causes Lyme borreliosis, most commonly ... -
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
(TAYLOR & FRANCIS INC, 2022)Although the therapeutic efficacy and commercial success of monoclonal antibodies (mAbs) are tremendous, the design and discovery of new candidates remain a time and cost-intensive endeavor. In this regard, progress in the ... -
A Proteomic Approach Provides New Insights into the Control of Soil-Borne Plant Pathogens by Bacillus Species
(Public Library Science, 2013)Beneficial microorganisms (also known as biopesticides) are considered to be one of the most promising methods for more rational and safe crop management practices. We used Bacillus strains EU07, QST713 and FZB24, and ... -
Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements
(Mdpi, 2019)Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous ROS production in normal cells is controlled by the appropriate regulation between the silver lining of low and high ROS concentration ... -
Salicylidene acylhydrazides attenuate survival of SH-SY5Y neuroblastoma cells through affecting mitotic regulator Speedy/RINGO and ERK/MAPK-PI3K/AKT signaling
(Humana Press Inc, 2020)Salicylidene acylhydrazide group synthetic compounds ME0053, ME005 and ME0192 are known for their iron chelating properties and due to these properties they are primarily used for blocking the bacterial type 3 secretory ... -
The screening of Digitalis ferruginea L. subsp. ferruginea for toxic capacities, phenolic constituents, antioxidant properties, mineral elements and proximate analysis
(SOC BRASILEIRA CIENCIA TECNOLOGIA ALIMENTOS, 2021)The present study outlines the antioxidant and toxic activity, total phenol, flavonoid and tannin content of Digitalis ferruginea?s extracts in addition to evaluating its proximate parameters and mineral elements. Successive ... -
Speedy/RINGO protein interacts with ERK/MAPK and PI3K/AKT pathways in SH-SY5Y neuroblastoma cells
(Springer, 2020)Abnormal activity of ERK/MAPK and PI3K/AKT pathways is one of the most important factors for the development of many cancer types including neuroblastoma cancer. Apart from these two pathways, some cell cycle regulators ... -
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
(SPRINGER, 2022)As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ... -
Syntheses, crystal structures, hirshfeld surface analyses and electrochemical etoposide/camptotechin sensor applications of acetaldehyde oxime derivatives
(Elsevier B.V., 2022)(E)-2-(4-Hydroxyphenyl)-2-oxoacetaldehyde oxime monohydrate (I) and (E)-2-(4-Nitrophenyl)-2-oxoacetaldehyde oximes (II) were synthesized from 4′-hydroxyacetophenone and 4′-nitroacetophenone, respectively. Their structures ... -
Synthesis of Adenine-based Fluorescent and Naked-eye Chemosensors: Specific DNA Probes for the Detection of Bacterial Pathogens
(Slovensko Kemijsko Drustvo, 2021)A rapid and confident tool to identify and diagnose bacterial pathogens with more accuracy using DNA as fingerprints is necessary. Herein, we report a smart chemosensor having a terminal adenine sticking to the thymine of ... -
Synthesis, Structural Investigations, and In Vitro/In Silico Bioactivities of Flavonoid Substituted Biguanide: A Novel Schiff Base and Its Diorganotin (IV) Complexes
(MDPI, 2022)Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological study of quercetin is extremely difficult due to its very low solubility. However, diorganotin complexes of quercetin are more ... -
Targeted mesoporous silica nanoparticles for improved inhibition of disinfectant resistant Listeria monocytogenes and lower environmental pollution
(Elsevier B.V., 2021)Benzalkonium chloride (BAC) is a common ingredient of disinfectants used for industrial, medical, food safety and domestic applications. It is a common pollutant detected in surface and wastewaters to induce adverse effects ... -
Targeting MDM2-p53 Axis through Drug Repurposing for Cancer Therapy: A Multidisciplinary Approach
(PMC, 2023)Cancer remains a major cause of morbidity and mortality worldwide, and while current therapies, such as chemotherapy, immunotherapy, and cell therapy, have been effective in many patients, the development of novel therapeutic ... -
Transcriptional analyses of the effects ofCatharanthus roseusL. medicinal plant extracts on some markers related to obesity and inflammation in 3T3-L1 mouse cell lines
(Springer, 2020)Catharanthus roseusL. (C. roseus) is one of the medicinal plants used to treat diabetes. In this study, 3T3-L1 preadipocyte cell lines which are fully differentiated into adipocytes were utilized and these were treated ... -
UPLC-ESI-MS/MS screening, potential of larvicide and antioxidant activity of bioactive compounds in gagea bohemica extracts
(Parlar Scientific Publications, 2020)This work was designed to phenolic compound analysis with UPLC-ESI-MS/MS (Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry), antioxidant and larvicidal (against Musca domestica and Culex pipiens) activities ...
