Başlık için Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu listeleme
Toplam kayıt 125, listelenen: 117-125
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STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
(SPRINGER, 2022)As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ... -
Syntheses, crystal structures, hirshfeld surface analyses and electrochemical etoposide/camptotechin sensor applications of acetaldehyde oxime derivatives
(Elsevier B.V., 2022)(E)-2-(4-Hydroxyphenyl)-2-oxoacetaldehyde oxime monohydrate (I) and (E)-2-(4-Nitrophenyl)-2-oxoacetaldehyde oximes (II) were synthesized from 4′-hydroxyacetophenone and 4′-nitroacetophenone, respectively. Their structures ... -
Synthesis of Adenine-based Fluorescent and Naked-eye Chemosensors: Specific DNA Probes for the Detection of Bacterial Pathogens
(Slovensko Kemijsko Drustvo, 2021)A rapid and confident tool to identify and diagnose bacterial pathogens with more accuracy using DNA as fingerprints is necessary. Herein, we report a smart chemosensor having a terminal adenine sticking to the thymine of ... -
Synthesis, Structural Investigations, and In Vitro/In Silico Bioactivities of Flavonoid Substituted Biguanide: A Novel Schiff Base and Its Diorganotin (IV) Complexes
(MDPI, 2022)Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological study of quercetin is extremely difficult due to its very low solubility. However, diorganotin complexes of quercetin are more ... -
Targeted mesoporous silica nanoparticles for improved inhibition of disinfectant resistant Listeria monocytogenes and lower environmental pollution
(Elsevier B.V., 2021)Benzalkonium chloride (BAC) is a common ingredient of disinfectants used for industrial, medical, food safety and domestic applications. It is a common pollutant detected in surface and wastewaters to induce adverse effects ... -
Targeting MDM2-p53 Axis through Drug Repurposing for Cancer Therapy: A Multidisciplinary Approach
(PMC, 2023)Cancer remains a major cause of morbidity and mortality worldwide, and while current therapies, such as chemotherapy, immunotherapy, and cell therapy, have been effective in many patients, the development of novel therapeutic ... -
Transcriptional analyses of the effects ofCatharanthus roseusL. medicinal plant extracts on some markers related to obesity and inflammation in 3T3-L1 mouse cell lines
(Springer, 2020)Catharanthus roseusL. (C. roseus) is one of the medicinal plants used to treat diabetes. In this study, 3T3-L1 preadipocyte cell lines which are fully differentiated into adipocytes were utilized and these were treated ... -
UPLC-ESI-MS/MS screening, potential of larvicide and antioxidant activity of bioactive compounds in gagea bohemica extracts
(Parlar Scientific Publications, 2020)This work was designed to phenolic compound analysis with UPLC-ESI-MS/MS (Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry), antioxidant and larvicidal (against Musca domestica and Culex pipiens) activities ... -
Xanthohumol: A Metabolite with Promising Anti-Neoplastic Potential
(Bentham Science Publishers, 2021)The overwhelming globalburden of cancer has posed numerous challenges and opportunities for developing anti-cancer therapies. Phytochemicalshave emerged as promising synergistic compounds with potential anti-cancer effects ...