Kurum Yazarı "Yıldız, Ayşegül" Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu İçin Listeleme
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Extracellular microRNAs: key players to explore the outcomes of in vitro fertilization
Khan, Haroon Latif; Bhatti, Shahzad; Abbas, Sana; Kaloǧlu, Celal; Isa, Ahmed Mostafa; Younas, Hooria; Ziders, Rachel; Yıldız, Ayşegül (BioMed Central Ltd, 2021)Background: MicroRNAs (miRNAs) are small RNA molecules that modulate post-transcriptional gene regulation. They are often used as promising non-invasive biomarkers for the early diagnosis of cancer. However, their roles ... -
p60-katanin: a novel interacting partner for p53
Korulu, Sirin; Yıldız, Ayşegül (Springer, 2020)Katanin, one of the best-characterized microtubule (MT) severing proteins, is composed of two subunits: catalytic p60-katanin, and regulatory p80-katanin. p60-katanin triggers MT reorganization by severing them. MT ... -
Speedy/RINGO protein interacts with ERK/MAPK and PI3K/AKT pathways in SH-SY5Y neuroblastoma cells
Kaya, Yeşim; Küçükvardar, Seren; Yıldız, Ayşegül (Springer, 2020)Abnormal activity of ERK/MAPK and PI3K/AKT pathways is one of the most important factors for the development of many cancer types including neuroblastoma cancer. Apart from these two pathways, some cell cycle regulators ... -
Targeting MDM2-p53 Axis through Drug Repurposing for Cancer Therapy: A Multidisciplinary Approach
Yıldız, Ayşegül; Ghafoor, Naeem Abdul (PMC, 2023)Cancer remains a major cause of morbidity and mortality worldwide, and while current therapies, such as chemotherapy, immunotherapy, and cell therapy, have been effective in many patients, the development of novel therapeutic ...