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dc.contributor.authorAtik, Hülya
dc.contributor.authorBülbül, Tuba
dc.contributor.authorÖzdemir, Vural
dc.contributor.authorAvcı, Gülcan
dc.contributor.authorBülbül, Aziz
dc.date.accessioned2020-11-20T14:29:59Z
dc.date.available2020-11-20T14:29:59Z
dc.date.issued2020
dc.identifier.issn0145-8884
dc.identifier.issn1745-4514
dc.identifier.urihttps://doi.org/10.1111/jfbc.13498
dc.identifier.urihttps://hdl.handle.net/20.500.12809/295
dc.descriptionWOS: 000574818600001en_US
dc.descriptionPubMed ID: 33015880en_US
dc.description.abstractAmong today's health problems, metabolic diseases are at the forefront. Hypothyroidism (HT) is a disease characterized by increased TSH, decreased T3&T4 concentrations in serum, with overall metabolic slowdown. Although there are many studies in the literature about oxidative status in HT, statements in these studies are contradictory. In our study, the effect of essential oils obtained from the leaves, flowers, and roots ofMyrtus communisL. on oxidative metabolism in an HT model induced by propylthiouracil (PTU) in rats was investigated. A total of 36 Wistar albino rats were randomly divided into six groups as follows: (1) Control, (2) PTU, (3)M. communisL. oil 200 (MO 200), (4)M. communisL. oil 400 (MO 400), (5) PTU + MO 200, and (6) PTU + MO 400. In our study, while oxidative status deteriorates in groups given PTU, antioxidant activity increases in groups givenM. communisL. oil. Practical applications Essential oils are aromatic oily liquids derived from different parts of plants.M. communisL. is one of the best-known herbs in the class of aromatic and medicinal plants. This paper emphasizes the effect ofM. communisL. oil on the negative oxidative state that occurs in HT conditions. The present study provides a positive effect of essential oils obtained from theM. communisL. on the oxidative state seen in HT. In light of this information, it may be beneficial to useM. communisL. oil due to its antioxidative effect in HT conditions.en_US
dc.description.sponsorshipAfyon Kocatepe University Scientific Research Projects Coordination UnitAfyon Kocatepe University [18.KARIYER.248]en_US
dc.description.sponsorshipAfyon Kocatepe University Scientific Research Projects Coordination Unit, Grant/Award Number: 18.KARIYER.248en_US
dc.item-language.isoengen_US
dc.publisherWileyen_US
dc.item-rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEssential Oilen_US
dc.subjectHypothyroidismen_US
dc.subjectOxidative Balanceen_US
dc.titleEffect of myrtle (Myrtus communisL.) essential oil on oxidant-antioxidant balance in rats with propylthiouracil-induced hypothyroidismen_US
dc.item-typearticleen_US
dc.contributor.departmentMÜ, Milas Veteriner Fakültesi, Zootekni Ve Hayvan Besleme Bölümüen_US
dc.contributor.departmentMÜ, Milas Veteriner Fakültesi, Temel Bilimler Bölümü
dc.contributor.institutionauthorBülbül, Tuba
dc.contributor.institutionauthorBülbül, Aziz
dc.identifier.doi10.1111/jfbc.13498
dc.relation.journalJournal of Food Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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