dc.contributor.author | Tanrıverdi, Özgür | |
dc.contributor.author | Arzıman, Süleyman | |
dc.contributor.author | Küçükvardar, S. | |
dc.contributor.author | Yıldız, Ayşegül | |
dc.date.accessioned | 2020-11-20T14:30:04Z | |
dc.date.available | 2020-11-20T14:30:04Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 0923-7534 | |
dc.identifier.issn | 1569-8041 | |
dc.identifier.uri | https://doi.org/10.1016/j.annonc.2020.08.174 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12809/344 | |
dc.description | ESMO Virtual Congress - SEP 19-OCT 18, 2020 - ELECTR NETWORK | en_US |
dc.description | WOS: 000573469100022 | en_US |
dc.description.abstract | Some lung cancer (LC) patients carry germline truncating mutations in DNA repair or other cancer-related genes, however it is unclear whether these allelic variants play a causative role in LC predisposition, or, alternatively, are occasionally present in these subjects due to a chance. Case-control comparison is often not efficient due to rarity of gene-inactivating variants in population, therefore alternative approaches are required. We evaluated whether germ-line inactivation of GPRC5A and CHEK2 genes facilitates LC in mice. | en_US |
dc.description.sponsorship | European Soc Med Oncol | en_US |
dc.description.sponsorship | Mugla Sitki Kocman University Scientific Research Project OfficeMugla Sitki Kocman University [17/023] | en_US |
dc.description.sponsorship | This work was supported by grant from the Mugla Sitki Kocman University Scientific Research Project Office (Project No: 17/023). | en_US |
dc.item-language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.item-rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Oncology | en_US |
dc.title | Salicylidene Acylhydrazides attenuate SH-SY5Y neuroblastoma cell survival through mitotic regulator Speedy/RINGO and ERK/ MAPK-PI3K/ AKT pathways | en_US |
dc.item-type | conferenceObject | en_US |
dc.contributor.department | MÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.identifier.volume | 31 | en_US |
dc.identifier.startpage | S251 | en_US |
dc.identifier.endpage | S251 | en_US |
dc.relation.journal | Annals of Oncology | en_US |
dc.relation.publicationcategory | Konferans Öğesi - Uluslararası - Kurum Öğretim Elemanı | en_US |