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dc.contributor.authorAlataş, Emine Tuğba
dc.contributor.authorBiteker, Murat
dc.contributor.authorAlataş, Ömer Doğan
dc.date.accessioned2020-11-20T14:30:06Z
dc.date.available2020-11-20T14:30:06Z
dc.date.issued2020
dc.identifier.issn0340-3696
dc.identifier.issn1432-069X
dc.identifier.urihttps://doi.org/10.1007/s00403-019-02032-6
dc.identifier.urihttps://hdl.handle.net/20.500.12809/356
dc.descriptionWOS: 000547255500002en_US
dc.descriptionPubMed ID: 31894390en_US
dc.description.abstractPrevious studies showed an association between various dermatological diseases and epicardial fat thickness (EFT). However, EFT, which has been accepted as a cardiometabolic risk factor in recent years, has not been studied in the context of hidradenitis suppurativa (HS). Therefore, we aimed to determine whether EFT is increased in HS patients, and whether EFT is associated with disease severity. Forty adult patients with HS and 100 age- and sex-matched controls were included. Patients with diabetes mellitus, cardiovascular diseases, chronic renal or hepatic diseases, or other inflammatory conditions were excluded. The EFT was measured by transthoracic echocardiography. Disease severity was assessed by Hurley stage, and stage III patients have been described as having severe disease. High-sensitivity C-reactive protein (hs-CRP) and EFT were significantly higher in HS patients compared to controls. There were positive correlations between EFT and the duration of the disease, hs-CRP, and Hurley stage. The EFT was proportionally increased in HS patients with increasing disease severity; the largest EFT was found in Hurley stage 3 patients (7.34 +/- 2.30 mm), followed by Hurley stage 2 patients (6.12 +/- 1.82 mm), and Hurley stage 1 patients (4.83 +/- 0.98 mm). Multivariate analysis showed that male gender, hs-CRP, body mass index, and EFT >= 5.9 mm were independent predictors of severe disease. The EFT is increased in HS, and it is an independent predictor of disease severity in adult patients with HS.en_US
dc.item-language.isoengen_US
dc.publisherSpringeren_US
dc.item-rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpicardial Fat Thicknessen_US
dc.subjectHidradenitis Suppurativaen_US
dc.titleEpicardial fat thickness is increased and associated with disease severity in hidradenitis suppurativaen_US
dc.item-typearticleen_US
dc.contributor.departmentMÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.contributor.departmentMÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.contributor.departmentMÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.contributor.institutionauthorAlataş, Emine Tuğba
dc.contributor.institutionauthorBiteker, Murat
dc.contributor.institutionauthorAlataş, Ömer Doğan
dc.identifier.doi10.1007/s00403-019-02032-6
dc.identifier.volume312en_US
dc.identifier.issue7en_US
dc.identifier.startpage467en_US
dc.identifier.endpage472en_US
dc.relation.journalArchives of Dermatological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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