| dc.contributor.author | Duru, Mehmet Emin | |
| dc.contributor.author | Tel, Gulsen | |
| dc.contributor.author | Öztürk, Mehmet | |
| dc.contributor.author | Harmandar, Mansur | |
| dc.date.accessioned | 2020-11-20T16:23:14Z | |
| dc.date.available | 2020-11-20T16:23:14Z | |
| dc.date.issued | 2012 | |
| dc.identifier.issn | 1307-6167 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12809/4231 | |
| dc.description | Tel-Cayan, Gulsen/0000-0002-1916-7391; Ozturk, Mehmet/0000-0001-8932-4535 | en_US |
| dc.description | WOS: 000299683800013 | en_US |
| dc.description.abstract | The essential oil from the aerial parts of Salvia chrysophylla Staph (Lamiaceae), endemic to Turkey, was investigated by using GC and GC-MS. Fifty-four of 55 components, represented 99.52% of the total oil, were identified. The major components of the essential oil were found to be alpha-terpinenyl acetate (36.31%), beta-caryophyllene (15.29%), linalool (8.12%) and beta-elemene (4.26%). The antioxidant activity of the oil was investigated by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and beta-carotene/linoleic acid tests. Anticholinesterase activity was screened against acetylcholinesterase and butyrylcholinesterase which are the chief enzymes of Alzheimer's disease. The essential oil showed weak antioxidant activity. However, at 1 mg/mL concentration, the essential oil exhibited mild acetylcholinesterase (52.5+/-2.0%) and moderate butyrylcholinesterase (76.5+/-2.7%) inhibitory activity | en_US |
| dc.description.sponsorship | Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TUBITAK-TBAG-106T095] | en_US |
| dc.description.sponsorship | Authors would like to thank The Scientific and Technological Research Council of Turkey (TUBITAK-TBAG-106T095) for financial support and Dr. Tuncay Dirmenci (Faculty of Necati Bey Education, Department of Biology Education, Balikesir University) for the identification of the plant sample. The Sitki Kocman Foundation (SKV) is also acknowledged by the authors. | en_US |
| dc.item-language.iso | eng | en_US |
| dc.publisher | Acg Publications | en_US |
| dc.item-rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Salvia Chrysophylla | en_US |
| dc.subject | Essential Oil | en_US |
| dc.subject | GC and GC-MS | en_US |
| dc.subject | Antioxidant Activity | en_US |
| dc.subject | Anticholinesterase Activity | en_US |
| dc.title | Chemical Composition, Antioxidant and Anticholinesterase Activities of the Essential Oil of Salvia chrysophylla Staph | en_US |
| dc.item-type | article | en_US |
| dc.contributor.department | MÜ | en_US |
| dc.contributor.departmentTemp | [Duru, Mehmet Emin; Tel, Gulsen; Ozturk, Mehmet; Harmandar, Mansur] Mugla Univ, Dept Chem, Fac Sci, TR-48121 Mugla, Turkey | en_US |
| dc.identifier.volume | 6 | en_US |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.startpage | 175 | en_US |
| dc.identifier.endpage | 179 | en_US |
| dc.relation.journal | Records of Natural Products | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
