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Methylation of cation-chloride cotransporters NKCC1 and KCC2 in patients with juvenile myoclonic epilepsy
(Springer-Verlag Italia Srl, 2019)
The etiology of juvenile myoclonic epilepsy (JME) is still unknown and the process of elaboration of multiple genetic mechanisms is ongoing. The aim of this study was to investigate the potential role of NKCC1 (SCL12A2) ...
Cinsel istismar olgularında monoamin oksidaz A enziminin gen polimorfizmi ve davranım bozukluğu gelişmesi ile arasındaki ilişkinin incelenmesi
(2017)
Amaç: Bu çalışmanın amacı cinsel istismar mağduru olan olgularda davranım bozukluğu (DB) geliştiren ve geliştirmeyen gruplar arasında monoamin oksidaz A (MAO-A) gen polimorfizmi açısından ilişki olup olmadığını incelemektir. ...
Differential expressions of cancer-associated genes and their regulatory miRNAs in colorectal carcinoma
(Elsevier Science Bv, 2015)
Colorectal cancer is one of the frequently seen malignancies in the world. To date, several oncogenes and tumor suppressor genes have been identified and linked to colorectal cancer pathogenesis. Although recent advances ...
Upregulation of SIRT1 gene in gastric adenocarcinoma
(Aves, 2019)
Background/Aims: SIRT1 gene overexpression is reportedly associated with cancer development, via the triggering of DNA repair impairment, and cell proliferation. The study aimed to investigate SIRT1 expression in patients ...
Insecticide imidacloprid influences cognitive functions and alters learning performance and related gene expression in a rat model
(Wiley, 2015)
The potential toxic effects of several pesticides, including imidacloprid on non-target organisms have not been clearly established. Also, the chronic effects of non-toxic doses on cognitive function in mammals are unknown. ...
Application of talcum powder, trichloroacetic acid and silver nitrate in female rats for non-surgical sterilization: evaluation of the apoptotic pathway mRNA and miRNA genes
(Wiley, 2015)
There are several methods used for non-surgical sterilization in birth control including quinacrine, trichloroacetic acid (TCA), erythromycin, tetracycline, silver nitrate and talcum powder. Among these, talcum powder, TCA ...
Changes in sirtuin 2 and sirtuin 3 mRNA expressions in rheumatoid arthritis
(Aves, 2017)
Objective: Sirtuins (SIRTs) play a prominent role in metabolism, apoptosis, aging, inflammation, and epigenetics. Inflammation, apoptosis, and epigenetics are pathogenic issues in rheumatoid arthritis (RA). This study aimed ...
INVESTIGATION OF REELIN RS7341475, RS362691 AND RS12705169 GENE POLYMORPHISMS IN CASES A WITH SUICIDE ATTEMPT
(Carbone Editore, 2015)
Background: Suicidal ideations and behavior is one of the most serious conditions among psychiatric emergencies. Neurobiology and genetics of suicide attracted more interest in subsequent period. Today, studies focus on ...
Determination of the effects on learning and memory performance and related gene expressions of clothianidin in rat models
(Springer, 2014)
Clothianidin (CLO) is one of the pesticides used to protect against insects, and its potential toxic effects on cognitive functions are not clearly known. This study aims to evaluate the possible effects of dose-dependent ...
Polymorphisms in ADAMTS4 and ADAMTS5 are not linked to susceptibility to knee osteoarthritis in the Turkish population
(Funpec-Editora, 2016)
Considering the functions of aggrecanase-1 (ADAMTS4) and -2 (ADAMTS5), which are thought to be the two major enzymes responsible for the destruction of aggrecans in arthritic diseases, we investigated whether important ...