Laboratuvar kaynakli bruselloz: Iki olgu sunumu

Abstract

Brucellosis is a zoonotic infectious disease caused by Brucella species, still endemic in our country affecting different organs and systems. Mainly it is transmitted by direct contact with an infected animal, unpasteurized milk and milk products from infected animals, and to laboratory personnel working with these bacteriae by direct contact or with aerosol inhalation. Therefore, beside livestock farmers and veterinarians, laboratory personnel are also under the risk of infection. Brucelossis is among the most common laboratory acquired infectious diseases in the world. However, laboratory acquired brucelossis cases are rarely reported in our country. In this report, two cases of laboratory acquired brucelossis in two microbiology laboratory personnel are presented. Both of the patients were female, presenting with fever, muscle and joint pain and no other findings on physical examination. Their hemogram and biochemistry parameters were within normal ranges, and their common feature was working with Brucella species bacteriae. The first patient was initially evaluated as viral infection and the final diagnosis was delayed for approximately two weeks. The second patient however, was diagnosed and treated on time based on our experience with the first patient. Both patients had postivie Brucella tube agglutination tests 1/1280 and 1/640 respectively and Brucella species microorganisms were isolated in the blood cultures. The patients were successfully treated with doxycicline (2 × 100mg) and rifampicin (1 × 600mg). As a result, we would like to remind that brucellosis might be transmited in the laboratory environment and in order to prevent the contamination the personnel must comply with the use of protective equipment. As for the clinicians, they should consider investigating brucellosis in laboratory personel presenting with fever.