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dc.contributor.authorÖzlek, B.
dc.contributor.authorÖzlek, E.
dc.contributor.authorTekinalp, M.
dc.contributor.authorKahraman, S.
dc.contributor.authorAğuş, H.Z.
dc.contributor.authorÇelik, O.
dc.contributor.authorBiteker, Murat
dc.date.accessioned2020-11-20T17:17:12Z
dc.date.available2020-11-20T17:17:12Z
dc.date.issued2019
dc.identifier.issn1368-5031
dc.identifier.urihttps://doi.org/10.1111/ijcp.13341
dc.identifier.urihttps://hdl.handle.net/20.500.12809/6318
dc.descriptionPubMed ID: 30865367en_US
dc.description.abstractObjectives: To compare real-world characteristics and management of individuals aged 80 and older with heart failure (HF) and mid-range ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF) derived from a large cohort of survey and to compare them with those younger than 80 from the same survey. Methods: This is an observational, multicentre and cross-sectional study conducted in Turkey (NCT03026114). Consecutive 1065 (mean age of 67.1 ± 10.6 years) patients admitted to the cardiology outpatient units with HFmrEF and HFpEF were included. Results: Participants aged 80 and older (n = 123, 11.5%) were more likely to be female (66.7% vs 52.5%, P = 0.003), had a higher prevalence of atrial fibrillation (49.6% vs 34%, P = 0.001), and anaemia (46.3% vs 33.4%, P = 0.005) than those who were younger than 80. N-terminal pro B-type natriuretic peptide levels were higher in those aged 80 and older than in those younger than 80 (1037 vs 550 pg/ml, P < 0.001). The prescription rates of HF medications (including in ACE-Is/ARBs, ?-blockers, MRAs, digoxin, ivabradine and diuretics) were similar (P > 0.05) in both groups. Octogenarians did not significantly differ from younger patients in the prevalence of HFmrEF (24.4% vs 22.9%) and HFpEF (75.6% vs 77.1%). Coronary artery disease was associated with HFmrEF (P < 0.05), whereas atrial fibrillation was associated with HFpEF (P < 0.05) in octogenarians. Conclusions: This study revealed that nearly 12% of the individuals with HFmrEF and HFpEF in this real-world sample were aged 80 and older. Participants aged 80 and older are more likely to be female and have more comorbidities than those who were younger than 80. However, HF medication profiles were similar in both groups. This study also showed that associated factors with HFmrEF and HFpEF were differ in octogenarians. © 2019 John Wiley & Sons Ltden_US
dc.item-language.isoengen_US
dc.publisherBlackwell Publishing Ltden_US
dc.item-rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleClinical features of heart failure with mid-range and preserved ejection fraction in octogenarians: Results of a multicentre, observational studyen_US
dc.item-typearticleen_US
dc.contributor.departmenten_US
dc.contributor.departmentTempÖzlek, B., Department of Cardiology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey; Özlek, E., Department of Cardiology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey; Tekinalp, M., Department of Cardiology, Kahramanmaras Necip Fazıl City Hospital, Kahramanmaras, Turkey; Kahraman, S., Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey; Ağuş, H.Z., Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey; Çelik, O., Department of Cardiology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey; Çil, C., Department of Cardiology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey; Kaya, B.C., Department of Cardiology, Mehmet Akif İnan Training and Research Hospital, Sanlıurfa, Turkey; Rencüzoğulları, İ., Department of Cardiology, Kafkas University Medical Faculty, Kars, Turkey; Mert, K.U., Department of Cardiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey; Çakır, M.O., Department of Cardiology, Bulent Ecevit Universiy Medical Faculty, Zonguldak, Turkey; Ösken, A., Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey; Bekar, L., Department of Cardiology, Hitit University Corum Erol Olcok Training and Research Hospital, Corum, Turkey; Çelik, Y., Department of Cardiology, Kirikkale Yuksek İhtisas Hospital, Kirikkale, Turkey; Başaran, Ö., Department of Cardiology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey; Doğan, V., Department of Cardiology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey; Mert, G.Ö., Department of Cardiology, Yunus Emre State Hospital, Eskisehir, Turkey; Sancar, K.M., Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey; Sevinç, S., Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey; Biteker, M., Department of Cardiology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkeyen_US
dc.identifier.doi10.1111/ijcp.13341
dc.identifier.volume73en_US
dc.identifier.issue4en_US
dc.relation.journalInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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