A new inflammatory marker for bone loss and low bone mineral density: Platelet-tolymphocyte ratio

Abstract

Aim: The aim of the study is to assess the possible relation of platelet-to-lymphocyte ratio (PLR), neutrophil-to-platelet ratio and low-density lipoprotein cholesterol levels with low bone mineral density (BMD) in postmenopausal women. Methodology: In total, 211 postmenopausal women were divided into two groups according to their T-score results. The control group consisted of 32 and BMD group consisted of 179 patients. Electronic records of the patients were analyzed retrospectively. Result(s): PLR was statistically significantly higher in the BMD group. According to receiver operating characteristic analysis, PLR was found to be a discriminative factor for low BMD. Conclusion: PLR level may predict low BMD with baseline measurement in postmenopausal women. © 2017 Future Medicine Ltd.