Fabrication of graphene/azobenzene-perylene diimide derivative modified electrochemical sensors for the dopamine detection based on full factorial experimental design

Abstract

In this study, carbon paste electrode (CPE) was modified with graphene and a novel azobenzene-perylene diimide derivative (P4SAc) and utilized for the dopamine detection. Electrochemical performances of modified electrochemical platforms were examined and graphene/P4SAc/CPE exhibited the highest increment in dopamine oxidation signal. Experimental parameters were optimized by using full factorial design and analytical characteristics were examined. As a result, a linear range was obtained in the concentration range of 5-100 mu M with a detection limit of 0.26 mu M (n = 3). The developed sensor was also applied for the dopamine detection in injection samples and very promising results were obtained. (C) 2019 Elsevier Ltd. All rights reserved.