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Adjuvant composite cold atmospheric plasma therapy increases antitumoral effect of doxorubicin hydrochloride
Baysal, Ömür; Kniazeva, Volha; Tzerkovsky, Dzmitry; Kornev, Alexander; Kostevitch, Serhei (PMC, 2023)Introduction: Cancer is a global health concern, with a significant impact on mortality rates. Despite advancements in targeted antitumor drugs, the development of new therapies remains challenging due to high costs and ... -
Bacterial volatile organic compounds and gene-induced host-defense pathways
Silme, Ragıp Soner; Baysal, Ömür (ELSEVIER, 2022)The microbial volatile organic compounds (VOCs) directly and/or indirectly play a role in plant/fungi-microbe interactions. A number of different bacterial VOCs have been identified, comprising polyaromatic hydrocarbons. ... -
Characterization of Pseudoperonospora cubensis isolates from Europe and Asia using ISSR and SRAP molecular markers
Polat, İlknur; Baysal, Ömür; Mercati, Francesco; Kitner, Miloslav; Cohen, Yigal; Lebeda, Ales; Carimi, Francesco (Springer, 2014)Downy mildew caused by Pseudoperonospora cubensis is a major disease of cucurbits worldwide. New genotypes of the pathogen have recently appeared in the USA, EU and Israel causing breakdown of genetic resistance, expansion ... -
Comparison of Antifungal Activity of Bacillus Strains against Fusarium graminearum In Vitro and In Planta
Jimenez-Quiros, Catherine; Okechukwu, Emeka C.; Hong, Yiguo; Baysal, Ömür; Tor, Mahmut (MDPI, 2022)Fusarium graminearum (Fg) causes Fusarium head blight (FHB) disease in wheat and barley. This pathogen produces mycotoxins including deoxynivalenol (DON), the T-2 and fumorisin B1. Translocation of the mycotoxins in grains ... -
Data mining and molecular dynamics analysis to detect HIV-1 reverse transcriptase RNase H activity inhibitor
Ghafoor, Naeem Abdul; Kırboğa, Kevser Kübra; Baysal, Ömür; Süzek, Barış Ethem; Silme, Ragıp Soner (nstitute for Ionics, 2023)HIV-1 is a deadly virus that affects millions of people worldwide. In this study, we aimed to inhibit viral replication by targeting one of the HIV-1 proteins and identifying a new drug candidate. We used data mining and ... -
The effect of a seed coating with Origanum vulgare essential oil on Clavibacter michiganensis subsp. michiganensis
Yılmaz, Meral; Baysal, Ömür; Silme, Ragıp Soner (Czech Academy of Agricultural Sciences, 2021)The study aimed to evaluate the efficacy of a seed film coating with Origanum vulgare Linnaeus essential oil (EO) against Clavibacter michiganensis subsp. michiganensis (Cmm) on tomatoes. Tomato seeds (cv. Rio Grande) ... -
GENETIC UNIFORMITY OF A SPECIFIC REGION IN SARS-CoV-2 GENOME AND REPURPOSING OF N-ACETYL-D-GLUCOSAMINE
Baysal, Ömür; Silme, Ragıp Soner; Karaaslan, Çağatay; Ignatov, Alexander N. (PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2021)The causative agent of the viral pneumonia outbreak in the world identified as SARS-CoV-2 leads to a severe respiratory illness like SARS and MERS. The pathogen spreading has turned into a pandemic dissemination and increased ... -
GENOMIC CHARACTERIZATION AND PHYTOSTIMULATIVE EFFECT OF A NOVEL SERRATIA SPECIES
Çetinkaya, Agit; Baysal, Ömür; Silme, Ragıp Soner; Azim, M. Kamran; Saleem, Faizan (Serbian Genetics Society, 2022)Some of non-pathogenic bacteria are effective biocontrol agents and plant growth inducers besides its degradative property on polycyclic aromatic hydrocarbons (PAH). Herein, we report a novel candidate Serratia species ... -
Host-Induced Gene Silencing: Approaches in Plant Disease Management
Baysal, Ömür; Baştaş, Kubilay Kurtuluş (Springer International Publishing, 2023)Crops exposed to the damage of various biotic and abiotic sources result in reduced yields and cause economic losses. There are prominent strategies such as breeding for improved resistance, the application of pesticides, ... -
Molecular dynamics analysis of N-acetyl-D-glucosamine against specific SARS-CoV-2’s pathogenicity factors
Baysal, Ömür; Ghafoor, Naeem Abdul; Silme, Ragıp Soner; Ignatov, Alexander N.; Kniazeva, Volha (Public Library of Science, 2021)The causative agent of the pandemic identified as SARS-CoV-2 leads to a severe respiratory illness similar to SARS and MERS with fever, cough, and shortness of breath symptoms and severe cases that can often be fatal. In ... -
The Prevalence and Genetic Characterization of Strains of Borrelia Isolated from Ixodes Tick Vectors in Belarus (2012-2019)
Kniazeva, Volha; Baysal, Ömür; Krasko, Anatoli; Iwaniak, Wojciech; Higgs, Stephen (Mary Ann Liebert, 2021)Borrelia burgdorferi sensu lato (s.l.) is the most common pathogen of medical significance transmitted by ticks of the family Ixodidae in Belarus. Human infection with B. burgdorferi causes Lyme borreliosis, most commonly ... -
The role of environmental factors and genetic diversity on colonization success of a non-native fish, Lepomis gibbosus from western part of Turkey
Ağdamar, Sevan; Tarkan, Ali Serhan; Keskin, Emre; Top, Nildeniz; Doğaç, Ersin; Baysal, Ömür; Emiroğlu, Özgür (Pergamon-Elsevier Science Ltd, 2015)Non-native freshwater fishes may become one of the dominant species in still and slow running waters and may impact whole ecosystem. One such species is the pumpkinseed Lepomis gibbosus, which has become widely distributed ... -
Soft computing model on genetic diversity and pathotype differentiation of pathogens: A novel approach
Gürüler, Hüseyin; Peker, Musa; Baysal, Ömür (Univ Catolica de Valparaiso, 2015)Background: Identifying and validating biomarkers' scores of polymorphic bands are important for studies related to the molecular diversity of pathogens. Although these validations provide more relevant results, the ... -
Synthesis of Adenine-based Fluorescent and Naked-eye Chemosensors: Specific DNA Probes for the Detection of Bacterial Pathogens
Şener, Burak; Baysal, Ömür; Nadeem, Said; Silme, Ragıp Soner (Slovensko Kemijsko Drustvo, 2021)A rapid and confident tool to identify and diagnose bacterial pathogens with more accuracy using DNA as fingerprints is necessary. Herein, we report a smart chemosensor having a terminal adenine sticking to the thymine of ...