Yazar "Aggarwal, Diwakar" için listeleme
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Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
Tuli, Hardeep Singh; Mittal, Sonam; Loka, Mariam; Aggarwal, Vaishali; Aggarwal, Diwakar; Masurkar, Akshara; Kaur, Ginpreet; Varol, Mehmet; Sak, Katrin; Kumar, Manoj; Sethi, Gautam; Bishayee, Anupam (Elsevier, 2021)Cancer is an anomalous growth and differentiation of cells known to be governed by oncogenic factors. Plant-based natural metabolites have been well recognized to possess chemopreventive properties. Deguelin, a natural ... -
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
Tuli, Hardeep Singh; Aggarwal, Vaishali; Tuorkey, Muobarak; Aggarwal, Diwakar; Parashar, Nidarshana Chaturvedi; Varol, Mehmet; Savla, Raj; Kaur, Ginpreet; Mittal, Sonam; Sak, Katrin (Elsevier, 2021)Oncogenic transformation has been the major cause of global mortality since decades. Despite established therapeutic regimes, majority of cancer patients either present with tumor relapse, refractory disease or therapeutic ... -
Gut Microbiota-Assisted Synthesis, Cellular Interactions and Synergistic Perspectives of Equol as a Potent Anticancer Isoflavone
Varol, Mehmet; Tuli, Hardeep Singh; Kumar, Ajay; Sak, Katrin; Aggarwal, Diwakar; Gupta, Dhruv Sanjay; Çapanoğlu,Esra (MDPI, 2022)It is well known that, historically, plants have been an important resource of anticancer agents, providing several clinically approved drugs. Numerous preclinical studies have shown a strong anticancer potential of ... -
Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements
Aggarwal, Vaishali; Tuli, Hardeep S.; Thakral, Falak; Singhal, Paavan; Aggarwal, Diwakar; Srivastava, Saumya; Sethi, Gautam; Pandey, Anjana; Sak, Katrin; Varol, Mehmet; Khan, Md. Asaduzzaman (Sage Publications Ltd, 2020)Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-spectrum applicability to prevent dreadful diseases such as cardiovascular disease, neurodegeneration, and cancer. The reported anticancer ... -
Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance
Tuli, Hardeep Singh; Mittal, Sonam; Aggarwal, Diwakar; Parashar, Gaurav; Parashar, Nidarshana Chaturvedi; Upadhyay, Sushil Kumar; Sharma, Anil Kumar; Varol, Mehmet (Academic Press, 2020)In the last few decades, targeting cancer by the use of dietary phytochemicals has gained enormous attention. The plausible reason and believe or mind set behind this fact is attributed to either lesser or no side effects ... -
Xanthohumol: A Metabolite with Promising Anti-Neoplastic Potential
Tuli, Hardep S; Aggarwal, Vaishali; Parashar, Gaurav; Aggarwal, Diwakar; Parashar, Nidarshana C; Tuorkey, Muobarak J; Varol, Mehmet; Sak, Katrin; Kumar, Manoj; Buttar, Harpal S. (Bentham Science Publishers, 2021)The overwhelming globalburden of cancer has posed numerous challenges and opportunities for developing anti-cancer therapies. Phytochemicalshave emerged as promising synergistic compounds with potential anti-cancer effects ...