Yazar "Altuntas, Irfan" için listeleme
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The effect of different intraarticular drug applications to the antioxidation system and lipid peroxidation in gonarthrosis
Aslan, Ahmet; Aydogan, Nevres Hurriyet; Ilhan, Mucahit; Ozerdemoglu, Remzi Arif; Altuntas, Irfan; Yorgancigil, Huseyin (Aves, 2012)Oxidative stress and lipid peroxidation may have a role in pathogenesis of knee osteoarthritis (gonarthrosis). In this study, we investigated both the role of disease mechanisms, lipid peroxidation and antioxidant defense ... -
Effects of chronic scopolamine administration on spatial working memory and hippocampal receptors related to learning
Doguc, Duygu K.; Delibas, Namik; Vural, Huseyin; Altuntas, Irfan; Sutcu, Recep; Sonmez, Yonca (Lippincott Williams & Wilkins, 2012)Scopolamine has been used in neuropsychopharmacology as a standard drug that leads to symptoms mimicking cognitive deficits seen during the aging process in healthy humans and animals. Scopolamine is known to be a nonselective ... -
Effects of Subchronic Treatment with Ibuprofen and Nimesulide on Spatial Memory and NMDAR Subunits Expression in Aged Rats
Bilgin, Ozlem Ozturk; Doguc, Duygu Kumbul; Altuntas, Irfan; Sutcu, Recep; Delibas, Namik (Shaheed Beheshti Univ, Sch Pharmacy, 2013)Several studies point to an important function of cyclooxygenase (COX) and prostaglandin signaling in models of synaptic plasticity which is associated with N-methyl-D-aspartate receptors (NMDARs). Cyclooxygenase gene is ... -
Silibinin attenuates methotrexate-induced pulmonary injury by targeting oxidative stress
Kalemci, Serdar; Topal, Yasar; Celik, Serkan Yasar; Yilmaz, Nigar; Beydilli, Halil; Kosar, Mehmet Ilkay; Altuntas, Irfan (Spandidos Publ Ltd, 2015)The aim of the present study was to assess the protective effect of silibinin against methotrexate (MTX)-induced pulmonary toxicity. Rats were divided into four groups (MTX, MTX + silibinin, silibinin and control. MTX was ...