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Effects of Subchronic Treatment with Ibuprofen and Nimesulide on Spatial Memory and NMDAR Subunits Expression in Aged Rats

Bilgin, Ozlem Ozturk; Doguc, Duygu Kumbul; Altuntas, Irfan; Sutcu, Recep; Delibas, Namik (Shaheed Beheshti Univ, Sch Pharmacy, 2013)

Several studies point to an important function of cyclooxygenase (COX) and prostaglandin signaling in models of synaptic plasticity which is associated with N-methyl-D-aspartate receptors (NMDARs). Cyclooxygenase gene is ...