Yazar "Celik, Sevim Karakas" için listeleme
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Association Analysis of CHRNA4 Gene Polymorphisms and Levels of Marker of Oxidative DNA Damage and Oxidative Stress in Migraine Patients
Edgunlu, Tuba Gokdogan; Turkcu, Ummuhani Ozel; Oz, Zehra Safi; Ozen, Banu; Kokturk, Furuzan; Celik, Sevim Karakas (Journal Neurological Sciences, 2013)Aim: Migraine is a primary headache syndrome which has been a genetic factor in quite complex etiopathogenesis. The mechanisms underlying the migraine have not been clearly enlightened. The aim of our study is to investigate ... -
The association of FOXO3A gene polymorphisms with serum FOXO3A levels and oxidative stress markers in vitiligo patients
Turkcu, Ummuhani Ozel; Tekin, Nilgun Solak; Edgunlu, Tuba Gokdogan; Celik, Sevim Karakas; Oner, Setenay (Elsevier, 2014)Vitiligo is an acquired epidermal pigment loss of the skin. Oxidative stress is one of the major theories in the pathophysiology of vitiligo. FOXO3A is the forkhead members of the class O (FOXO) transcription factors, and ... -
Genetic variants of estrogen beta and leptin receptors may cause gynecomastia in adolescent
Eren, Erdal; Edgunlu, Tuba; Korkmaz, Huseyin Anil; Cakir, Esra Deniz Papatya; Demir, Korcan; Cetin, Esin Sakalli; Celik, Sevim Karakas (Elsevier Science Bv, 2014)Objective: Gynecomastia is a benign breast enlargement in males that affects approximately one-third of adolescents. The exact mechanism is not fully understood; however, it has been proposed that estrogen receptors and ... -
Genetic variants of synaptic vesicle and presynaptic plasma membrane proteins in idiopathic generalized epilepsy
Yilmaz, Mustafa; Edgunlu, Tuba Gokdogan; Yilmaz, Nigar; Cetin, Esin Sakalli; Celik, Sevim Karakas; Emir, Gulser Karadaban; Sozen, Ayse (Taylor & Francis Ltd, 2014)Background: The aim of this study was to analyze the role of the genetic variants of two synaptic vesicle proteins (VAMP2 and Synaptotagmin XI) and two presynaptic plasma membrane proteins (Syntaxin 1A and SNAP-25) in ... -
Novel SNARE Complex Polymorphisms Associated with Multiple Sclerosis: Signs of Synaptopathy in Multiple Sclerosis
Yalin, Osman Ozgur; Edgunlu, Tuba Gokdogan; Celik, Sevim Karakas; Emre, Ufuk; Gunes, Taskin; Erdal, Yuksel; Unal, Aysun Eroglu (Galenos Yayincilik, 2019)Background: It is well known that axonal degeneration plays a role in disability in patients with multiple sclerosis, and synaptopathy has recently become an important issue. Aims: To investigate the possible roles of ... -
Prodynorphin (PDYN) gene polymorphisms in Turkish patients with methamphetamine use disorder, changes in PDYN serum levels in withdrawal and the relationship between PDYN, temperament and depression
Senormanci, Guliz; Turan, Cetin; Celik, Sevim Karakas; Celik, Aycan; Gökdoğan Edgünlü, Tuba; Akbaş, Dilek; Senormanci, Omer (Routledge Journals, Taylor & Francis Ltd, 2020)Aim of the study is to compare prodynorphin (PDYN) rs1997794, rs1022563, rs6045819, rs2235749 polymorphisms in individuals with methamphetamine use disorder (MD) to that of healthy controls (HC), and to investigate the ... -
Variant Analysis of the Sirtuin (SIRT1) Gene in Multiple Sclerosis
Edgunlu, Tuba Gokdogan; Celik, Sevim Karakas; Emre, Ufuk; Unal, Aysun Eroglu; Dursun, Ahmet (Kuwait Medical Assoc, 2013)Objective: Multiple sclerosis (MS) is an inflammatory demyelinating disease affecting the central nervous system. Although the exact pathogenesis of MS is unknown, it is generally considered to be an autoimmune disease, ...
