Yazar "Edgunlu, Tuba Gokdogan" için listeleme
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Association Analysis of CHRNA4 Gene Polymorphisms and Levels of Marker of Oxidative DNA Damage and Oxidative Stress in Migraine Patients
Edgunlu, Tuba Gokdogan; Turkcu, Ummuhani Ozel; Oz, Zehra Safi; Ozen, Banu; Kokturk, Furuzan; Celik, Sevim Karakas (Journal Neurological Sciences, 2013)Aim: Migraine is a primary headache syndrome which has been a genetic factor in quite complex etiopathogenesis. The mechanisms underlying the migraine have not been clearly enlightened. The aim of our study is to investigate ... -
The association of FOXO3A gene polymorphisms with serum FOXO3A levels and oxidative stress markers in vitiligo patients
Turkcu, Ummuhani Ozel; Tekin, Nilgun Solak; Edgunlu, Tuba Gokdogan; Celik, Sevim Karakas; Oner, Setenay (Elsevier, 2014)Vitiligo is an acquired epidermal pigment loss of the skin. Oxidative stress is one of the major theories in the pathophysiology of vitiligo. FOXO3A is the forkhead members of the class O (FOXO) transcription factors, and ... -
Does the X-Chromosome Carry the Gene Responsible for Bipolar Disorder?
Edgunlu, Tuba Gokdogan; Duvarci, Ibrahim; Cetin, Esin Sakalli (Kure Iletisim Grubu A S, 2013)According to family, twin and adoption studies, which consistently indicate a strong genetic component, the specific genes that are responsible for bipolar disorder remain unclear. While the mode of transmission is poorly ... -
Genetic Variants of Synaptic Vesicle and Presynaptic Plasma Membrane Proteins In Alzheimer's Disease
Edgunlu, Tuba Gokdogan; Ozge, Aynur; Yalin, Osman Ozgur; Kul, Seval; Erdal, Mehmet Emin (Galenos Yayincilik, 2012)Background: Alzheimer's disease (AD) is the most common cause of dementia in the elderly, and its etiology is still not fully understood. The aim of this study was to analyze the role of the genetic variants of two synaptic ... -
Genetic variants of synaptic vesicle and presynaptic plasma membrane proteins in idiopathic generalized epilepsy
Yilmaz, Mustafa; Edgunlu, Tuba Gokdogan; Yilmaz, Nigar; Cetin, Esin Sakalli; Celik, Sevim Karakas; Emir, Gulser Karadaban; Sozen, Ayse (Taylor & Francis Ltd, 2014)Background: The aim of this study was to analyze the role of the genetic variants of two synaptic vesicle proteins (VAMP2 and Synaptotagmin XI) and two presynaptic plasma membrane proteins (Syntaxin 1A and SNAP-25) in ... -
Molecular Investigation of Staphylococcal Cassette Chromosome Mec Types and Genotypic Relations of Methicillin-Resistant Staphylococci Isolated from Before and after Hospital Exposed Students
Ekinci, Bora; Edgunlu, Tuba Gokdogan; Bayramoglu, Gulcin; Atay, Gulsen Ulucam (Wolters Kluwer Medknow Publications, 2018)Background: Reservoir of methicillin resistance genes called staphylococcal cassette chromosome mec (SCCmec), plasmids and genomic characterisations of isolates have been widely investigated in epidemiologic research. ... -
Novel SNARE Complex Polymorphisms Associated with Multiple Sclerosis: Signs of Synaptopathy in Multiple Sclerosis
Yalin, Osman Ozgur; Edgunlu, Tuba Gokdogan; Celik, Sevim Karakas; Emre, Ufuk; Gunes, Taskin; Erdal, Yuksel; Unal, Aysun Eroglu (Galenos Yayincilik, 2019)Background: It is well known that axonal degeneration plays a role in disability in patients with multiple sclerosis, and synaptopathy has recently become an important issue. Aims: To investigate the possible roles of ... -
The relationship DRD3 Ser9Gly polymorphisms and cognitive functions in schizophrenia: a preliminary study
Varma, Gulfizar Sozeri; Karadag, Filiz; Erdal, Mehmet Emin; Ay, Ozlem Izci; Aydin, Emel; Edgunlu, Tuba Gokdogan; Herken, Hasan (Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2012)Objective: Dopamine is a neurotransmitter that plays an important role in the etiopathogenesis of schizophrenia and cognitive functions. The aim of this study was to investigate the effects of the Ser9Gly polymorphisms of ... -
The Role of Forkhead Box Class O3A and SIRT1 Gene Variants in Early-Onset Psoriasis
Pektas, Suzan Demir; Dogan, Gursoy; Edgunlu, Tuba Gokdogan; Karakas-Celik, Sevim; Ermis, Esra; Tekin, Nilgun Solak (Medknow Publications & Media Pvt Ltd, 2018)Background: Psoriasis is a chronic inflammatory skin disorder, which is characterized by a heightened immunological response. Although the immunogenetics of this chronic inflammatory disorder is poorly understood, its ... -
Sirtuin gene polymorphisms are associated with chronic obstructive pulmonary disease in patients in Mugla province
Kalemci, Serdar; Edgunlu, Tuba Gokdogan; Kara, Murat; Turkcu, Ummuhani Ozel; Cetin, Esin Sakalli; Zeybek, Arife (Termedia Publishing House Ltd, 2014)Introduction: Chronic obstructive pulmonary disease (COPD) is an irreversible progressive chronic inflammatory disease that causes shortness of breath in consequence of a decrease in pulmonary functions. The pulmonary ... -
Variant Analysis of the Sirtuin (SIRT1) Gene in Multiple Sclerosis
Edgunlu, Tuba Gokdogan; Celik, Sevim Karakas; Emre, Ufuk; Unal, Aysun Eroglu; Dursun, Ahmet (Kuwait Medical Assoc, 2013)Objective: Multiple sclerosis (MS) is an inflammatory demyelinating disease affecting the central nervous system. Although the exact pathogenesis of MS is unknown, it is generally considered to be an autoimmune disease, ...
