Yazar "Erdal, Mehmet Emin" için listeleme
-
Association of Adult Attention Deficit Hyperactivity Disorder With Dopamine Transporter Gene, Dopamine D3 Receptor, and Dopamine D4 Receptor Gene Polymorphisms
Sevinç, Erinç; Erdal, Mehmet Emin; Şengul, Cem; Cakaloz, Burcu; Ergündü, Tuba; Herken, Hasan (Kure Iletisim Grubu A S, 2010)Objective: Attention deficit hyperactivity disorder (ADHD) is a developmental disorder which is characterized by inattention, impulsiveness, and hyperactivity. The etiology of ADHD is not completely understood, but it is ... -
Association of SNAP-25 Gene Ddel and Mnll Polymorphisms with Adult Attention Deficit Hyperactivity Disorder
Herken, Hasan; Erdal, Mehmet Emin; Kenar, Ayşe Nur Inci; Ünal, Gonca Ayşe; Çakaloz, Burcu; Ay, Mustafa Ertan; Şengül, Cem; Edgünlü, Tuba (Korean Neuropsychiatric Assoc, 2014)Objective The synaptosomal-associated protein of 25 kDa (SNAP-25) gene is a presynaptic plasma membrane protein and an integral component of the vesicle docking and fusion machinery mediating secretion of neurotransmitters. ... -
Association of Synapsin III Gene with Adult Attention Deficit Hyperactivity Disorder
İnci Kenar, Ayşe Nur; Edgünlü, Tuba; Herken, Hasan; Erdal, Mehmet Emin (Mary Ann Liebert, Inc, 2013)It was aimed to investigate the association of the synapsin III gene -196 G> A and -631 C>G polymorphisms that takes place in an encoding presynaptic protein, with adult attention deficit hyperactivity disorder (ADHD). One ... -
Diagnostic Value of MiR-125b as a Potential Biomarker for Stage I Lung Adenocarcinoma
Zeybek, Arife; Öz, Necdet; Kalemci, Serdar; Edgünüu, Tuba; Kızıltuğ, Mehmet Tuğhan; Tosun, Kürşad; Erdal, Mehmet Emin (Bentham Science Publ Ltd, 2019)Background: We aimed at exploring biological functions of differentially expressed miRNAs during carcinogenesis, to identify miRNAs dysegulations involved in DNA repair mechanisms, and to evaluate potential of miRNAs as ... -
Emotional schemas and their relationship with clinical characteristics in patients with alcohol dependence
Amaç: Alzheimer Hastalığı (AH) ileri yaşlarda kendini demansla gösteren etyolojisi henüz net olarak tanımlanmamış nörolojik bir hastalıktır. Sinaptik bölgede çok sayıda molekül salınmaktadır. Salınan bu moleküllerin AH ... -
Genetic Variants of Synaptic Vesicle and Presynaptic Plasma Membrane Proteins In Alzheimer's Disease
Edgunlu, Tuba Gokdogan; Ozge, Aynur; Yalin, Osman Ozgur; Kul, Seval; Erdal, Mehmet Emin (Galenos Yayincilik, 2012)Background: Alzheimer's disease (AD) is the most common cause of dementia in the elderly, and its etiology is still not fully understood. The aim of this study was to analyze the role of the genetic variants of two synaptic ... -
miR-181a-5p is a potential candidate epigenetic biomarker in multiple sclerosis
Edgünlü, Tuba; Görücü Yılmaz, Şenay; Emre, Ufuk; Taşdelen, Bahar; Kuru, Oktay; Kutlu, Gülnihal; Erdal, Mehmet Emin (NLM (Medline), 2022)Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and axonal degeneration. Abnormal expression of microRNAs (miRNAs) plays an important role in MS ... -
miR-181a-5p is a potential candidate epigenetic biomarker in sclerosis
Edgünlü, Tuba; Görücü Yılmaz, Şenay; Emre, Ufuk; Taşdelen, Bahar; Kuru, Oktay; Kutlu, Gülnihal; Erdal, Mehmet Emin (CANADIAN SCIENCE PUBLISHING, 2022)Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and axonal degeneration. Abnormal expression of microRNAs (miRNAs) plays an important role in MS ... -
The relationship DRD3 Ser9Gly polymorphisms and cognitive functions in schizophrenia: a preliminary study
Varma, Gulfizar Sozeri; Karadag, Filiz; Erdal, Mehmet Emin; Ay, Ozlem Izci; Aydin, Emel; Edgunlu, Tuba Gokdogan; Herken, Hasan (Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2012)Objective: Dopamine is a neurotransmitter that plays an important role in the etiopathogenesis of schizophrenia and cognitive functions. The aim of this study was to investigate the effects of the Ser9Gly polymorphisms of ... -
The role of Wnt pathway antagonists in early-stage lung adenocarcinoma
Zeybek, Arife; Öz, Necdet; Kalemci ,Serdar; Tosun, Kürşad; Gökdoğan Edgünlü, Tuba; Kızıltuğ, Mehmet Tuğhan; Tekin, Leyla; Erdal, Mehmet Emin (Springer, 2021)Purpose We aimed to examine the expression levels of the genes encoding adenomatous polyposis coli (APC) 1, APC-2, Dickkopf related protein (DKK)-1, DKK-3, secreted frizzled-related protein (SFRP)-2, SFRP-4, and SFRP-5, ... -
Şizofrenide DRD3 ser9gly polimorfizmlerinin bilişsel işlevlerle ilişkisi: Bir ön çalışma
Sözerivarma, Gülfizar; Karadağ, Rukiye Filiz; Aydın, Emel; Erdal, Mehmet Emin; İzciay, Özlem; Herken, Hasan; Gökdoğanedgünlü, Tuba (2012)Amaç: Dopamin şizofreni etiyopatogenezinde ve bilişsel işlevlerde önemli rolü olan bir nörotransmitterdir. Bu çalışma- da, şizofreni hastalarında dopamin reseptör 3 (DRD3) Ser9Gly polimorfizmi ile klinik belirtiler ve ...
