Yazar "Ghafoor, Naeem Abdul" için listeleme
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Data mining and molecular dynamics analysis to detect HIV-1 reverse transcriptase RNase H activity inhibitor
Ghafoor, Naeem Abdul; Kırboğa, Kevser Kübra; Baysal, Ömür; Süzek, Barış Ethem; Silme, Ragıp Soner (nstitute for Ionics, 2023)HIV-1 is a deadly virus that affects millions of people worldwide. In this study, we aimed to inhibit viral replication by targeting one of the HIV-1 proteins and identifying a new drug candidate. We used data mining and ... -
Molecular dynamics analysis of N-acetyl-D-glucosamine against specific SARS-CoV-2’s pathogenicity factors
Baysal, Ömür; Ghafoor, Naeem Abdul; Silme, Ragıp Soner; Ignatov, Alexander N.; Kniazeva, Volha (Public Library of Science, 2021)The causative agent of the pandemic identified as SARS-CoV-2 leads to a severe respiratory illness similar to SARS and MERS with fever, cough, and shortness of breath symptoms and severe cases that can often be fatal. In ... -
Targeting MDM2-p53 Axis through Drug Repurposing for Cancer Therapy: A Multidisciplinary Approach
Yıldız, Ayşegül; Ghafoor, Naeem Abdul (PMC, 2023)Cancer remains a major cause of morbidity and mortality worldwide, and while current therapies, such as chemotherapy, immunotherapy, and cell therapy, have been effective in many patients, the development of novel therapeutic ...
