Yazar "Kolak, Ufuk" için listeleme
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Anticholinesterase and Antioxidant Activities of Natural Abietane Diterpenoids with Molecular Docking Studies
Topcu, Gulacti; Akdemir, Atilla; Kolak, Ufuk; Öztürk, Mehmet; Boga, Mehmet; Bahadori, Fatemeh; Cakmar, Seda Damla Hatipoglu (Bentham Science Publ Ltd, 2020)Background: Alzheimer's Disease (AD) is one of the most prevalent causes of dementia in the world, and no drugs available that can provide a complete cure. Cholinergic neurons of the cerebral cortex of AD patients are lost ... -
Antioxidant abietane diterpenoids from Salvia barrelieri
Kabouche, Ahmed; Kabouche, Zahia; Öztürk, Mehmet; Kolak, Ufuk; Topçu, Gülaçtı (Elsevier Sci Ltd, 2007)The root extract of endemic Algerian Salvia species Salvia barrelieri Ettling and its diterpenoids were investigated for potential antioxidant activity. From its acetone extract, a new natural abietane diterpenoid ... -
Antioxidant activity of Erica arborea
Ay, Mehmet; Bahadori, Fatemeh; Oeztuerk, Mehmet; Kolak, Ufuk; Topcu, Guelacti (Elsevier Science Bv, 2007)The antioxidant properties of the methanol extract of leaves and flowers of Erica arborea and the ethyl acetate, butanol and water soluble fractions were investigated. The ethyl acetate extract was found to be the richest ... -
Antioxidant activity tests on novel triterpenoids from Salvia macrochlamys
Topcu, Guelactu; Ertas, Abdulselam; Kolak, Ufuk; Oeztuerk, Mehmet; Ulubelen, Ayhan (Arkat Usa Inc, 2007)The methanol extract of Salvia macrochlamys Boiss. and Kotschy was fractionated on a silica gel column to yield a group of terpenic compounds. After separation and cleaning, seven known and three new terpenoid compounds ... -
Antioxidant and anticholinesterase active constituents from Micromeria cilicica by radical-scavenging activity-guided fractionation
Öztürk, Mehmet; Kolak, Ufuk; Topçu, Gülaçtı; Öksüz, Sevil; Choudhary, M. Iqbal (Elsevier Sci Ltd, 2011)From the acetone extract of Micromeria cilicica, two new (1 and 2) and five known (3-7) compounds were obtained through radical-scavenging activity guided isolation. Structures of the compounds were identified as piperitone ... -
Antioxidant and anticholinesterase constituents of Salvia poculata
Kolak, Ufuk; Hacıbekiroğlu, Işıl; Öztürk, Mehmet; Özgökçe, Fevzi; Topçu, Gülaçtı; Ulubelen, Ayhan (Scientific Technical Research Council Turkey-Tubitak, 2009)Two triterpenoids, namely 2 alpha,3 alpha-dihydroxy-24-nor-4(23), 12-oleanadien-28-oic acid (1) and ursolic acid (2); 4. avonoids, namely 5-hydroxy-7,4'-dimethoxyflavone (3), cirsimaritin (4), eupatilin (5), and salvigenin ... -
Antioxidant Diterpenoids from the Roots of Salvia barrelieri
Kolak, Ufuk; Kabouche, Ahmed; Öztürk, Mehmet; Kabouche, Zahia; Topçu, Gülaçtı; Ulubelen, Ayhan (John Wiley & Sons Ltd, 2009)Introduction - The phytochemical and biological studies carried out on Salvia species showed that their extracts and constituents have various biological activities. Objective - The aim of this study was the isolation of ... -
Development and Validation of a Novel LC–MS/MS Method for the Quantitation of 19 Fingerprint Phytochemicals in Salvia Species: A Chemometric Approach
Yılmaz, Mustafa Abdullah; Ertaş, Abdulselam; Yener, İsmail; Tokul Ölmez, Özge; Fırat, Mehmet; Temel, Hamdi; Öztürk, Mehmet; Kolak, Ufuk (Oxford Academic, 2021)Being traditionally utilized mainly as appetizers and herbal teas as well as used to ease abdominal pains, colds and gastrointestinal issues, the genus Salvia L. has gained significant consideration owing to its remarkable ... -
Essential Oil, Aroma, and Fatty Acid Profiles of Five Endemic Salvia Taxa from Turkey with Chemometric Analysis
Ertaş, Abdulselam; Akdeniz, Mehmet; Yener, İsmail; Öztürk, Mehmet; Tokul Ölmez, Özge; Fırat, Mehmet; Kolak, Ufuk (Wiley, 2021)The essential oil, aroma, and fatty acid compositions of Salvia cerino-pruinosa var. cerino-pruinosa, S. cerino-pruinosa var. elazigensis, S. pseudeuphratica, S. rosifolia, and S. kurdica collected in 2015, 2016, and 2017 ... -
Fatty acids and other lipid composition of five Trifolium species with antioxidant activity
Sabudak, Temine; Öztürk, Mehmet; Goren, Ahmet C.; Kolak, Ufuk; Topcu, Gulacti (Taylor & Francis Ltd, 2009)The contents of fatty acids and other lipids of Trifolium balansae Boiss, Trifolium stellatum Lin., Trifolium nigrescens Viv. subsp. petrisavi (Clem) Holmboe, Trifolium constantinopolitanum Ser., and Trifolium resupinatum ... -
GC-MS Analysis and Antimicrobial Activity of Essential Oil of Stachys cretica subsp smyrnaea
Öztürk, Mehmet; Duru, Mehmet Emin; Aydoğmuş-Öztürk, Fatma; Harmandar, Mansur; Mahlıçlı, Melda; Kolak, Ufuk; Ulubelen, Ayhan (Natural Products Inc, 2009)The essential oil from the aerial parts of Stachys cretica L. subsp. smyrnaea Rech. fil. (Lamiaceae), endemic to Turkey, was investigated by using GC and GC-MS. Thirty-four of 37 components, represented 99.7% of the total ... -
GC-MS Analysis of the Antioxidant Active Fractions of Micromeria juliana with Anticholinesterase Activity
Öztürk, Mehmet; Kolak, Ufuk; Duru, Mehmet Emin; Harmandar, Mansur (Natural Products Inc, 2009)The aerial parts of Micromeria juliana (L.) Bentham ex Reichb. were extracted with light petroleum, acetone and methanol, successively. The antioxidant activity of different concentrations of the extracts was evaluated ... -
Investigation of Anticholinesterase Activity of a Series of Salvia Extracts and the Constituents of Salvia staminea
Topcu, Gulacti; Kolak, Ufuk; Öztürk, Mehmet; Boga, Mehmet; Hatipoglu, Seda Damla; Bahadori, Fatemeh; Dirmenci, Tuncay (Bentham Science Publ, 2013)In continuation of our studies on the genus Salvia fourteen alcoholic extracts of Salvia species were evaluated for their anticholinesterase activity. Among them, the most active extract at 200 mu g/mL was found to be S. ... -
Selective in vitro and in silico enzymes inhibitory activities of phenolic acids and flavonoids of food plants: Relations with oxidative stress
Yener, Ismail; Kocakaya, Safak Ozhan; Ertas, Abdulselam; Erhan, Bahadir; Kaplaner, Erhan; Oral, Elif Varhan; Kolak, Ufuk (Elsevier Sci Ltd, 2020)In this study, the inhibitory potentials of food originated 34 phenolic acids, and flavonoid compounds were screened against acetylcholinesterase, butyrylcholinesterase, urease, and tyrosinase enzymes. All compounds included ... -
Selective in-vitro Enzymes' Inhibitory Activities of Fingerprints Compounds of Salvia Species and Molecular Docking Simulations
Kocakaya, Safak Ozhan; Ertas, Abdulselam; Yener, Ismail; Ercan, Bahadir; Oral, Elif Varhan; Akdeniz, Mehmet; Kolak, Ufuk; Kaplaner, Erhan; Topcu, Gulacti (Shaheed Beheshti Univ, Sch Pharmacy, 2020)Recently Nutrition and Food Chemistry researches have been focused on plants and their products or their secondary metabolites having anti-alzheimer, anti-cancer, anti-aging, and antioxidant properties. Among these plants ... -
Terpenoids, essential oil composition and fatty acids profile, and biological activities of Anatolian Salvia fruticosa Mill.
Topcu, Gulacti; Öztürk, Mehmet; Kusman, Tuba; Barla Demirkoz, Ayse Asli; Kolak, Ufuk; Ulubelen, Ayhan (Scientific Technical Research Council Turkey-Tubitak, 2013)The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., afforded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ... -
Terpenoids, essential oil composition, fatty acid pro?le, and biological activities of Anatolian Salvia fruticosa Mill.
Topçu, Gülaçtı; Öztürk, Mehmet; Kuşman, Tuğba; Demirkoz, Ayşe Aslı Barla; Kolak, Ufuk; Ulubelen, Ayhan (2013)The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., a?orded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ...