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Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease

Gök, Müslüm; Madrer, Nimrod; Zorbaz, Tamara; Bennett, Estelle R.; Greenberg, David; Bennett, David A.; Soreq, Hermona (PMC, 2022)

Acetylcholinesterase and butyrylcholinesterase (AChE and BChE) are involved in modulating cholinergic signaling, but their roles in Alzheimer's and Parkinson's diseases (AD and PD) remain unclear. We identified a higher ...