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Dental Pulp Inflammation Initiates the Occurrence of Mast Cells Expressing the α1 and β1 Subunits of Soluble Guanylyl Cyclase
Korkmaz, Yüksel; Plomann, Markus; Puladi, Behrus; Demirbaş, Ayşegül; Bloch, Wilhelm (MDPI, 2023)The binding of nitric oxide (NO) to heme in the β1 subunit of soluble guanylyl cyclase (sGC) activates both the heterodimeric α1β1 and α2β1 isoforms of the enzyme, leading to the increased production of cGMP from GTP. In ...