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Effects of chronic scopolamine administration on spatial working memory and hippocampal receptors related to learning
Doguc, Duygu K.; Delibas, Namik; Vural, Huseyin; Altuntas, Irfan; Sutcu, Recep; Sonmez, Yonca (Lippincott Williams & Wilkins, 2012)Scopolamine has been used in neuropsychopharmacology as a standard drug that leads to symptoms mimicking cognitive deficits seen during the aging process in healthy humans and animals. Scopolamine is known to be a nonselective ... -
Effects of Subchronic Treatment with Ibuprofen and Nimesulide on Spatial Memory and NMDAR Subunits Expression in Aged Rats
Bilgin, Ozlem Ozturk; Doguc, Duygu Kumbul; Altuntas, Irfan; Sutcu, Recep; Delibas, Namik (Shaheed Beheshti Univ, Sch Pharmacy, 2013)Several studies point to an important function of cyclooxygenase (COX) and prostaglandin signaling in models of synaptic plasticity which is associated with N-methyl-D-aspartate receptors (NMDARs). Cyclooxygenase gene is ...