Yazar "Topcu, Gulacti" için listeleme
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Anticholinesterase and Antioxidant Activities of Natural Abietane Diterpenoids with Molecular Docking Studies
Topcu, Gulacti; Akdemir, Atilla; Kolak, Ufuk; Öztürk, Mehmet; Boga, Mehmet; Bahadori, Fatemeh; Cakmar, Seda Damla Hatipoglu (Bentham Science Publ Ltd, 2020)Background: Alzheimer's Disease (AD) is one of the most prevalent causes of dementia in the world, and no drugs available that can provide a complete cure. Cholinergic neurons of the cerebral cortex of AD patients are lost ... -
Antioxidant and Anticholinesterase Activities of Some Dialkylamino Substituted 3-Hydroxyflavone Derivatives
Culhaoglu, Burcu; Capan, Asli; Boga, Mehmet; Öztürk, Mehmet; Ozturk, Turan; Topcu, Gulacti (Bentham Science Publ Ltd, 2017)Background: Flavones, are a class of naturally occuring polyphenolic compounds which have 2-phenylchromen-4-one structure. Various studies showed that flavones have several pharmacological activities such as antioxidant, ... -
Antioxidant and Tyrosinase Inhibitory Activities of Flavonoids from Trifolium nigrescens Subsp petrisavi
Demirkiran, Ozlem; Sabudak, Temine; Öztürk, Mehmet; Topcu, Gulacti (Amer Chemical Soc, 2013)Trifolium nigrescens was researched for its chemical constituents for the first time. Bioassay-guided isolation of the EtOAc extract from the leaves of T. nigrescens resulted in the purification of a new biflavone, 4"',5,5 ... -
Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities
Tel, Gülsen; Öztürk, Mehmet; Mehmet, Emin Duru; Harmandar, Mansur; Topcu, Gulacti (Pergamon-Elsevier Science Ltd, 2010)The essential oil and methyl ester of hexane extract of Salvia chionantha Boiss. were analysed by GC and GC-MS. Totally, 54 components were detected in the essential oil and all of them were fully determined. Germacrene D ... -
Ent-kaurane diterpenoids isolated from Sideritis congesta
Topcu, Gulacti; Ertas, Abdulselam; Öztürk, Mehmet; Dincel, Demet; Kilic, Turgut; Halfon, Belkis (Elsevier Science Bv, 2011)A new ent-kaurane diterpenoid, together with eight known ent-kauranes, were isolated from the petroleum ether and acetone extracts of the whole plant of Sideritis congesta P. H. Davis & Hub.-Mor. and their structures were ... -
Evaluation of fruit extracts of six Turkish Juniperus species for their antioxidant, anticholinesterase and antimicrobial activities
Öztürk, Mehmet; Tumen, Ibrahim; Uğur, Aysel; Aydogmus-Ozturk, Fatma; Topcu, Gulacti (Wiley, 2011)BACKGROUND: Juniperus L. (Cupressaceae) species are mostly spread out in the Northern Hemisphere of the world, and some of them are used as folkloric medicines. The fruits of some species are eaten. Since oxidative stress ... -
Fatty acids and other lipid composition of five Trifolium species with antioxidant activity
Sabudak, Temine; Öztürk, Mehmet; Goren, Ahmet C.; Kolak, Ufuk; Topcu, Gulacti (Taylor & Francis Ltd, 2009)The contents of fatty acids and other lipids of Trifolium balansae Boiss, Trifolium stellatum Lin., Trifolium nigrescens Viv. subsp. petrisavi (Clem) Holmboe, Trifolium constantinopolitanum Ser., and Trifolium resupinatum ... -
Investigation of Anticholinesterase Activity of a Series of Salvia Extracts and the Constituents of Salvia staminea
Topcu, Gulacti; Kolak, Ufuk; Öztürk, Mehmet; Boga, Mehmet; Hatipoglu, Seda Damla; Bahadori, Fatemeh; Dirmenci, Tuncay (Bentham Science Publ, 2013)In continuation of our studies on the genus Salvia fourteen alcoholic extracts of Salvia species were evaluated for their anticholinesterase activity. Among them, the most active extract at 200 mu g/mL was found to be S. ... -
Phenolic compounds from Trifolium echinatum Bieb. and investigation of their tyrosinase inhibitory and antioxidant activities
Sabudak, Temine; Demirkiran, Ozlem; Öztürk, Mehmet; Topcu, Gulacti (Pergamon-Elsevier Science Ltd, 2013)Two bischromones, 3,3'-dimethoxy-2'-oxychromone (1), 3,3'-dihydroxy-2,2'-oxychromone (2) and a biflavone, 5,7,4',5 '',3''',4''''-hexahydroxy-3 ''-O-beta-glucosyl-3',7 ''-O-biflavone (3) have been isolated from whole plant ... -
Selective in-vitro Enzymes' Inhibitory Activities of Fingerprints Compounds of Salvia Species and Molecular Docking Simulations
Kocakaya, Safak Ozhan; Ertas, Abdulselam; Yener, Ismail; Ercan, Bahadir; Oral, Elif Varhan; Akdeniz, Mehmet; Kolak, Ufuk; Kaplaner, Erhan; Topcu, Gulacti (Shaheed Beheshti Univ, Sch Pharmacy, 2020)Recently Nutrition and Food Chemistry researches have been focused on plants and their products or their secondary metabolites having anti-alzheimer, anti-cancer, anti-aging, and antioxidant properties. Among these plants ... -
Terpenoids, essential oil composition and fatty acids profile, and biological activities of Anatolian Salvia fruticosa Mill.
Topcu, Gulacti; Öztürk, Mehmet; Kusman, Tuba; Barla Demirkoz, Ayse Asli; Kolak, Ufuk; Ulubelen, Ayhan (Scientific Technical Research Council Turkey-Tubitak, 2013)The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., afforded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ...
