Yazar "Turkcu, Ummuhani Ozel" için listeleme
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Association Analysis of CHRNA4 Gene Polymorphisms and Levels of Marker of Oxidative DNA Damage and Oxidative Stress in Migraine Patients
Edgunlu, Tuba Gokdogan; Turkcu, Ummuhani Ozel; Oz, Zehra Safi; Ozen, Banu; Kokturk, Furuzan; Celik, Sevim Karakas (Journal Neurological Sciences, 2013)Aim: Migraine is a primary headache syndrome which has been a genetic factor in quite complex etiopathogenesis. The mechanisms underlying the migraine have not been clearly enlightened. The aim of our study is to investigate ... -
The association of FOXO3A gene polymorphisms with serum FOXO3A levels and oxidative stress markers in vitiligo patients
Turkcu, Ummuhani Ozel; Tekin, Nilgun Solak; Edgunlu, Tuba Gokdogan; Celik, Sevim Karakas; Oner, Setenay (Elsevier, 2014)Vitiligo is an acquired epidermal pigment loss of the skin. Oxidative stress is one of the major theories in the pathophysiology of vitiligo. FOXO3A is the forkhead members of the class O (FOXO) transcription factors, and ... -
Carnosine supplementation protects rat brain tissue against ethanol-induced oxidative stress
Turkcu, Ummuhani Ozel; Bilgihan, Ayse; Biberoglu, Gursel; Caglar, Oznur Mertoglu (Springer, 2010)Ethanol causes oxidative stress and tissue damage. The aim of this study was to investigate the effect of antioxidant carnosine on the oxidative stress induced by ethanol in the rat brain tissue. Forty male rats were divided ... -
Day and Night Effect of Single Dose of Ionising Radiation and Melatonin Treatment of Lung Tissue of Rats
Guney, Yildiz; Uluoglu, Canan; Hicsonmez, Ayse; Turkcu, Ummuhani Ozel; Ozbey, Gul; Bilgihan, Ayse; Zengil, Hakan (Walter de Gruyter Gmbh, 2008)Objectives: We investigated the day-night differences in oxidative-injury and the inflammatory response in rat lung following total body irradiation by measuring thiobarbituric acid reactive substances levels and myeloperoxidase ... -
The Effect of Erythropoietin on Anastomotic Healing of Irradiated Rats
Turkcu, Ummuhani Ozel; Cakmak, Guldeniz Karadeniz; Demir, Ebru Ofluoglu; Bakkal, Hakan; Oner, Muzaffer Onder; Okyay, Rahsan Dilek; Ciftcioglu, Mehmet Akif (Taylor & Francis Inc, 2012)Aim: The aim of the present study is to evaluate the possible protective effects of erythropoietin (EPO) on anastomotic wound healing after preoperative radiotherapy according to its pleiotropic mechanism of action. Methods: ... -
The effect of zinc on ethanol-induced oxidative stress in rat liver
Caglar, Oznur Mertoglu; Bilgihan, Ayse; Turkcu, Ummuhani Ozel; Biberoglu, Gursel; Take, Gulnur (Walter de Gruyter Gmbh, 2012)Aim Zinc is known as an essential trace element and has antioxidant functions. This study was planned to investigate the effects of zinc on oxidative stress induced by ethanol in the rat liver tissue. Methods: Thirty-nine ... -
Effects of carbon dioxide pneumoperitoneum on hepatic function in obstructive jaundice: an experimental study in a rat model
Bostanci, Erdal Birol; Yol, Sinan; Teke, Zafer; Kayaalp, Cuneyt; Sakaogullari, Zisan; Turkcu, Ummuhani Ozel; Akoglu, Musa (Springer, 2010)The physiology of the patient during laparoscopy differs from that of open surgery. Both pneumoperitoneum and obstructive jaundice impair the hepatic function, but the combined insult has not been previously examined. In ... -
Effects of erdosteine on cyclosporine-A-induced hepatotoxicity in rats
Erarslan, Elife; Ekiz, Fuat; Uz, Burak; Koca, Cemile; Turkcu, Ummuhani Ozel; Bayrak, Reyhan; Delibasi, Tuncay (Taylor & Francis Ltd, 2011)Cyclosporine A (CsA) is a potent immunosuppressive agent used for organ transplantations and various autoimmune disorders. However, hepatotoxicity due to CsA remains one of the major side effects. The use of antioxidants ... -
Effects of Ozone Oxidative Preconditioning on Liver Regeneration after Partial Hepatectomy in Rats
Gultekin, Fatma Ayca; Cakmak, Guldeniz Karadeniz; Turkcu, Ummuhani Ozel; Yurdakan, Gamze; Demir, F. Ebru Ofluoglu; Comert, Mustafa (Taylor & Francis Inc, 2013)Aim: Similar protective effect of ischemic and ozone oxidative preconditioning (OzoneOP) in hepatic ischemia-reperfusion (I/R) injury was demonstrated, providing evidences that both preconditioning settings shared similar ... -
Effects of ozone preconditioning on recovery of rat colon anastomosis after preoperative radiotherapy
Tasdoven, Ilhan; Emre, Ali Ugur; Gultekin, Fatma Ayca; Oner, Muzaffcr Onder; Bakkal, Bekir Hakan; Turkcu, Ummuhani Ozel; Tasdoven, Gulin Ergun (Wroclaw Medical Univ, 2019)Background. Anastomotic leakage is a devastating complication of colorectal surgery. Neoadjuvant radiotherapy for colorectal cancer can affect the mechanical and biochemical parameters of anastomotic healing. It has been ... -
N-Acetyl-Cysteine Improves Anastomotic Wound Healing after Radiotherapy in Rats
Demir, Ebru Ofluoglu; Cakmak, Guldeniz Karadeniz; Bakkal, Hakan; Turkcu, Ummuhani Ozel; Kandemir, Nilufer; Demir, Ayse Semra; Tascilar, Oge (Taylor & Francis Inc, 2011)Aim: This study was designed to determine the effects of intraperitoneally or orally administered N-acetylcysteine (NAC) on anastomotic healing of irradiated rats. Methods: Thirty-two male Wistar albino rats were randomized ... -
Protection by L-carnitine against radiation-induced ileal mucosal injury in the rat: Pattern of oxidative stress, apoptosis and cytokines
Akpolat, Meryem; Gulle, Kanat; Topcu-Tarladacalisir, Yeter; Oz, Zehra Safi; Bakkal, Bekir Hakan; Arasli, Mehmet; Turkcu, Ummuhani Ozel (Taylor & Francis Ltd, 2013)Purpose : In this study, we tested the effects of L-carnitine (LC) on radiation-induced ileal mucosal damage. Materials and methods : Thirty Wistar albino rats were divided into five groups. The control group received ... -
Sirtuin gene polymorphisms are associated with chronic obstructive pulmonary disease in patients in Mugla province
Kalemci, Serdar; Edgunlu, Tuba Gokdogan; Kara, Murat; Turkcu, Ummuhani Ozel; Cetin, Esin Sakalli; Zeybek, Arife (Termedia Publishing House Ltd, 2014)Introduction: Chronic obstructive pulmonary disease (COPD) is an irreversible progressive chronic inflammatory disease that causes shortness of breath in consequence of a decrease in pulmonary functions. The pulmonary ...
