Yazar "Zengin, Talip" için listeleme
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Analysis of genomic and transcriptomic variations as prognostic signature for lung adenocarcinoma
Zengin, Talip; Önal-Süzek, Tuğba (Bmc, 2020)BackgroundLung cancer is the leading cause of the largest number of deaths worldwide and lung adenocarcinoma is the most common form of lung cancer. In order to understand the molecular basis of lung adenocarcinoma, ... -
Comparison of the effect of different glide path files on amount of apically extruded debris in curved root canals
Zengin, Talip; Kurt, Özge; Üstün, Yakup (John Wiley and Sons Inc, 2023)It is essential to create a glide path before root canal preparation with nickel–titanium rotary files to avoid file breakage and preserve the original canal structure. The aim of this study was to compare the amount of ... -
Comprehensive Profiling of Genomic and Transcriptomic Differences between Risk Groups of Lung Adenocarcinoma and Lung Squamous Cell Carcinoma
Zengin, Talip; Önal Süzek, Tuğba (MDPI, 2021)Lung cancer is the second most frequently diagnosed cancer type and responsible for the highest number of cancer deaths worldwide. Lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) are subtypes of ... -
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
Akbar, Rahmad; Bashour , Habib; Rawat, Puneet; Robert, Philippe A.; Zengin, Talip (TAYLOR & FRANCIS INC, 2022)Although the therapeutic efficacy and commercial success of monoclonal antibodies (mAbs) are tremendous, the design and discovery of new candidates remain a time and cost-intensive endeavor. In this regard, progress in the ... -
Synthesis, Crystal Structure, Hirshfeld Surface Analysis, DNA/BSA Interaction and Molecular Docking Studies of 2-(6-(4-chlorophenyl)-1,2,4-triazin-3-yl)quinoline
Göktürk, Tolga; Zengin, Talip; Hökelek, Tuncer; Gökçe Topkaya, Cansu; Güp, Ramazan (Elsevier B.V., 2023)We reported herein a new 1,2,4-triazine derivative, 2-(6-(4-chlorophenyl)-1,2,4-triazin-3-yl)quinoline, synthesized by cyclization of p‑chloro isonitrosophenylhydrazine with 2-quinolinecarboxaldehyde. Its structure was ...