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Toplam kayıt 193, listelenen: 181-190
Association between the anthropometric measurements and dietary habits on telomere shortening in healthy older adults: A-cross-sectional study
(John Wiley and Sons Inc, 2023)
im: This study aimed to evaluate the effect of anthropometric measurements and dietary habits on telomere length in healthy older residents in rural and urban areas. Methods: This was a cross-sectional study. The study ...
Downregulation of Yap1 during limb regeneration results in defective bone formation in axolotl
(Elsevier Inc., 2023)
The Hippo pathway plays an imperative role in cellular processes such as differentiation, regeneration, cell migration, organ growth, apoptosis, and cell cycle. Transcription coregulator component of Hippo pathway, YAP1, ...
Survival outcomes of hypomethylating agents maintenance therapy in new diagnosed AML patients: Real experience data
(PMC, 2022)
Objective: Acute myeloid leukemia (AML) is a hematological malignancy that frequently affects elderly population. With introducing the hypomethylating agents (HMAs) in elderly AML treatment, survival rates and quality of ...
Assessment of biological rhythm disturbances and emotion recognition in individuals with or without obstructive sleep apnea syndrome: The role of eating patterns
(Taylor and Francis Ltd., 2023)
Although a vast amount of research efforts including a plethora of distinct methodologies have been put forth, the pathophysiology of obstructive sleep apnea syndrome (OSAS) has not been compromised and multidimensional ...
Conversion of specific lncRNAs to biomarkers in exhaled breath condensate samples of patients with advanced stage non-small-cell lung cancer
(PMC, 2023)
Lung cancer (LC) is one of the most prevalent cancers with the highest fatality rate worldwide. Long noncoding RNAs (lncRNAs) are being considered potential new molecular targets for early diagnosis, follow-up, and individual ...
Hydroquinidine displays a significant anticarcinogenic activity in breast and ovarian cancer cells via inhibiting cell-cycle and stimulating apoptosis
(TUBITAK, 2023)
Breast and ovarian cancers are women’s most commonly diagnosed cancers. Seeking an efficient anticarcinogenic compound is still a top priority regarding the aggressiveness of these cancers and the limited benefit of current ...
The effects of PKI-402 on breast tumor models' radiosensitivity via dual inhibition of PI3K/mTOR
(INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2023)
PurposePI3K/Akt/mTOR pathway activation causes relapse and resistance after radiotherapy in breast cancer (BC). We aimed to radiosensitize BC cell lines to irradiation (IR) by PKI-402, a dual PI3K/mTOR inhibitor.MethodsWe ...
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease
(Journal of Chemical Neuroanatomy, 2023)
Background: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that primarily affects the motor system. Although there are several treatments available to alleviate PD symptoms, there is ...
Antioxidant and anti-inflammatory potential of crocin on the doxorubicin mediated hepatotoxicity in Wistar rats
(Elsevier Ltd, 2023)
Doxorubicin (DXR) is widely used in cancer treatment. However, it has not yet been possible to prevent the side effects of DXR. The aim of this study was to investigate the hepatoprotective effect of crocin against DXR ...
In vitro anti-carcinogenic effect of andarine as a selective androgen receptor modulator on MIA-PaCa-2 cells by decreased proliferation and cell-cycle arrest at G0/G1 phase
(Elsevier Ltd, 2023)
Pancreatic cancer (PC) continues to be devastating due to its highly malignant nature and poor prognosis. The limited benefits of the chemotherapeutic drugs and increasing resistance pose a critical challenge to overcome ...