Güncel Gönderiler: Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu
Toplam kayıt 125, listelenen: 21-40
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Synthesis, Structural Investigations, and In Vitro/In Silico Bioactivities of Flavonoid Substituted Biguanide: A Novel Schiff Base and Its Diorganotin (IV) Complexes
(MDPI, 2022)Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological study of quercetin is extremely difficult due to its very low solubility. However, diorganotin complexes of quercetin are more ... -
Licorice ( Glycyrrhiza glabra L.)-Derived Phytochemicals Target Multiple Signaling Pathways to Confer Oncopreventive and Oncotherapeutic Effects
(Dove Press, 2022)Cancer is a highly lethal disease, and its incidence has rapidly increased worldwide over the past few decades. Although chemotherapeutics and surgery are widely used in clinical settings, they are often insufficient to ... -
In vitro Regeneration and Synthetic Seed Production of Colchicum cilicicum Grown Naturally in Turkey
(Gıda, Tarım ve Hayvancılık Bakanlığı, 2022)Colchicum belongs to the Colchicaceae family and is naturally distributed in Turkey with 36 taxa. Colchicum species is known for both its medicinal aromatic and ornamental properties. In this study, Colchicum cilicium corms ... -
Gut Microbiota-Assisted Synthesis, Cellular Interactions and Synergistic Perspectives of Equol as a Potent Anticancer Isoflavone
(MDPI, 2022)It is well known that, historically, plants have been an important resource of anticancer agents, providing several clinically approved drugs. Numerous preclinical studies have shown a strong anticancer potential of ... -
Evaluation of Critical Points for Effective Cryopreservation of Four Different Citrus spp. Germplasm
(MDPI, 2022)The different pre- and post-treatments are critical in cryopreservation procedures and affect the shoot tip regrowth after freezing. In the present study, the long-term storage of four citrus cultivars [Bodrum Mandarin ... -
Morphological and molecular notes of Gypsophila pilulifera
(MAGNOLIA PRESS, 2022)A detailed study of the Turkish endemic Gypsophila pilulifera were presented by both morphological and molecular investigations of several sites (each one divided in four biotopes). The characteristics were investigated ... -
Antiproliferative and antioxidant potential of methanol extracts of aerial parts of Colchicum boissieri and Colchicum balansae
(Pamukkale University, 2022)The antiproliferative and antioxidant activities, and total phenolic, flavonoid, and tannin contents of methanol extracts obtained from the aerial parts of Colchicum boissieri and Colchicum balansae were investigated in ... -
Comparison of Antifungal Activity of Bacillus Strains against Fusarium graminearum In Vitro and In Planta
(MDPI, 2022)Fusarium graminearum (Fg) causes Fusarium head blight (FHB) disease in wheat and barley. This pathogen produces mycotoxins including deoxynivalenol (DON), the T-2 and fumorisin B1. Translocation of the mycotoxins in grains ... -
Potential cancer treatment effects of brusatol or eriodictyol combined with 5-fluorouracil (5-FU) in colorectal cancer cell
(SPRINGER, 2022)Colorectal cancer is among the most frequently diagnosed cancers in patients today. In the treatment of this disease, combination or multicomponent therapy has been identified as a potential method to improve patient ... -
GENOMIC CHARACTERIZATION AND PHYTOSTIMULATIVE EFFECT OF A NOVEL SERRATIA SPECIES
(Serbian Genetics Society, 2022)Some of non-pathogenic bacteria are effective biocontrol agents and plant growth inducers besides its degradative property on polycyclic aromatic hydrocarbons (PAH). Herein, we report a novel candidate Serratia species ... -
Syntheses, crystal structures, hirshfeld surface analyses and electrochemical etoposide/camptotechin sensor applications of acetaldehyde oxime derivatives
(Elsevier B.V., 2022)(E)-2-(4-Hydroxyphenyl)-2-oxoacetaldehyde oxime monohydrate (I) and (E)-2-(4-Nitrophenyl)-2-oxoacetaldehyde oximes (II) were synthesized from 4′-hydroxyacetophenone and 4′-nitroacetophenone, respectively. Their structures ... -
Antimicrobial screening to molecular docking of newly synthesized ferrocenyl-substituted pyrazole
(QASSIM UNIV, 2022)Objective: Microbial diseases are snowballing at an alarming proportion. Therefore, the intent of this study was to inspect the antimicrobial action of ferrocenyl-substituted pyrazole against various human pathogenic ... -
In vitro DNA interaction, topoisomerase I/II Inhibition and cytotoxic properties of polymeric copper(II) complex bridged with perchlorate ion containing N-4-type schiff base ligand
(Elsevier, 2022)Cu(II) complex containing p-Cl-isonitrosoacetophenone based on N 4-type Schiff base ligand was synthesized and characterized by elemental analysis, FTIR, H-1 NMR, (13) C NMR and UV-Visible. The crystal structure of the ... -
Metal nanoparticles in cancer: from synthesis and metabolism to cellular interactions
(SPRINGER HEIDELBERG, 2022)Nanotechnology has encouraged new and amended materials (metal nanoparticles) for therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) are versatile nanoscale entities, widely used to ... -
Phenolic profile, antioxidant, and antiproliferative activities of Convolvulus aucheri Choisy
(MILITARY MEDICAL ACAD-INI, 2022)Background/Aim. It is known that some members of the genus Convolvulus (C) L. are commonly used in Turkish folk medicine. These species are powerful in curing toothache and joint pains. Due to the limited information on ... -
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
(SPRINGER, 2022)As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ... -
Bacterial volatile organic compounds and gene-induced host-defense pathways
(ELSEVIER, 2022)The microbial volatile organic compounds (VOCs) directly and/or indirectly play a role in plant/fungi-microbe interactions. A number of different bacterial VOCs have been identified, comprising polyaromatic hydrocarbons. ... -
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
(TAYLOR & FRANCIS INC, 2022)Although the therapeutic efficacy and commercial success of monoclonal antibodies (mAbs) are tremendous, the design and discovery of new candidates remain a time and cost-intensive endeavor. In this regard, progress in the ... -
Cellular targets and molecular activity mechanisms of bee venom in cancer: recent trends and developments
(TAYLOR & FRANCIS INC, 2022)Bee venom therapy is known as a traditional approach to curing many medical conditions such as arthritis, pain and rheumatism. Bee venom also provides promising potential for treating many cancers such as breast, lung, ... -
Paclitaxel Delivery by Cationic Gelatin Nanoparticles
(WILEY-V C H VERLAG GMBH, 2022)Biodegradable polymeric nanoparticles have gained importance since they improve the therapeutic value of various water insoluble drugs and bioactive molecules by improving bioavailability, solubility and retention time. ...
