Güncel Gönderiler: Tıp Fakültesi
Toplam kayıt 1632, listelenen: 121-140
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Hydroquinidine displays a significant anticarcinogenic activity in breast and ovarian cancer cells via inhibiting cell-cycle and stimulating apoptosis
(TUBITAK, 2023)Breast and ovarian cancers are women’s most commonly diagnosed cancers. Seeking an efficient anticarcinogenic compound is still a top priority regarding the aggressiveness of these cancers and the limited benefit of current ... -
COVID-19’da D Vitamini ve Sekonder İnfeksiyon İlişkisi
(BILIMSEL TIP YAYINEVI, 2023)Giriş: D vitamini sitokin salınımı, inflamasyon, doğal ve edinsel bağışıklığın modülasyonunda görev yapmaktadır. Pandeminin başların- da SARS-CoV-2’ye bağlı gelişen akut respiratuvar distres sendromu veya diğer organ ... -
Therapeutic role of melatonin on acrylamide-induced hepatotoxicity in pinealectomized rats: Effects on oxidative stress, NF-κB signaling pathway, and hepatocellular proliferation
(Elsevier Ltd, 2023)Acrylamide (AA) is formed in some foods by the cooking process at high temperatures, and it could be a carcinogen in humans and rodents. The purpose of the current study was to reveal the possible protective effects of ... -
Mistletoe (Viscum album L.) extract attenuates ıtraconazole-ınduced acute oxidative stress and hepatocellular ınjury in rats
(UNIV KARACHI, 2023)In the current study, the protective effect of a mistletoe extract (Helixor (R), HLX) on Itraconazole (ITZ)-induced hepatocellular injury and acute oxidative stress in rats was aimed to be investigated by histological, ... -
Gastrostomy in Hospitalized Patients with Acute Stroke: "NoroTek" Turkey Point Prevalence Study Subgroup Analysis
(TURKISH NEUROLOGICAL SOC, 2023)Objective: Nutritional status assessment, dysphagia evaluation and enteral feeding decision are important determinants of prognosis in acute neurovascular diseases. Materials and Methods: NoroTek is a point prevalence study ... -
Novel activity of human BChE: Lipid hydrolysis
(ELSEVIER FRANCE, 2023)Acetylcholinesterase and butyrylcholinesterase (BChE) typically hydrolyze the neurotransmitter acetylcholine. The multifunctional enzyme BChE is associated with lipid metabolism through an undefined mechanism. Based on ... -
Obesity and the Mother Goddess of Neolithic Çatalhöyük
(Springer Science and Business Media Deutschland GmbH, 2023)Letter to Editor -
The relationship between coronavirus disease-2019-positive patients and plasma interleukins and transforming growth factor-β levels
(Wolters Kluwer Medknow Publications, 2023)Objective: The aim of this study is to reveal the relationship between the cytokine plasma levels and symptoms of coronavirus disease-2019 (COVID-19)-positive patients, which is characterized by serious respiratory syndromes. ... -
Crocin treatment exerts anti-inflammatory and anti-oxidative effects in liver tissue damage of pinealectomized diabetic rats
(Springer Science and Business Media Deutschland GmbH, 2023)Diabetes mellitus (DM) is a chronic metabolic disorder with an increasing global prevalence that leads to significant morbidity and mortality. The liver plays a vital role in glycemic regulation in physiological and ... -
How Did the Updated 2019 European Society of Cardiology/European Atherosclerosis Society Risk Categorization for Patients with Diabetes Affect the Risk Perception and Lipid Goals? A Simulated Analysis of Real-life Data from EPHESUS Study
(Turkish Society of Cardiology, 2023)Background: The recent 2019 European Society of Cardiology/European Atherosclerosis Society practice guidelines introduced a new risk categorization for patients with diabetes. We aimed to compare the implications of the ... -
Single-session repair of multiple pressure ulcers in non-ambulatory patients
(NLM (Medline), 2023)OBJECTIVE: Pressure ulcers (PUs) are highly prevalent and challenging wounds. In this study, patients with either tetraplegia or paraplegia, all of whom had multiple grade 4 PUs and who underwent single-session surgical ... -
Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
(The Texas Heart Institute, 2023)Background: Cilostazol is a guideline-recommended drug that improves intermittent claudication and quality of life in patients with chronic atherosclerotic peripheral arterial disease. The drug is used for most etiologies ... -
Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy
(PMC, 2023)Background: There is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent kinase 4/6 inhibitor (CDK4/6) based therapy. We aimed to evaluate which ... -
miR-181a-5p is a potential candidate epigenetic biomarker in sclerosis
(CANADIAN SCIENCE PUBLISHING, 2022)Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and axonal degeneration. Abnormal expression of microRNAs (miRNAs) plays an important role in MS ... -
Working memory ımprovement after transcranial direct current stimulation paired with working memory training ın diabetic peripheral neuropathy
(Routledge, 2023)Association of cognitive deficits and diabetic peripheral neuropathy (DPN) is frequent. Working memory (WM) deficits result in impairment of daily activities, diminished functionality, and treatment compliance. Mounting ... -
Appropriateness of aspirin use among diabetic patients in primary prevention of atherosclerotic cardiovascular diseases: an analysis of the ASSOS study
(Verduci Editore s.r.l, 2023)OBJECTIVE: Aspirin is an essential drug in the prevention of atherosclerotic cardiovascular disease (ASCVD). It is ultimately indicated in a patient with ASCVD. However, its role is debated in primary prevention. We aimed ... -
BİR AİLE SAĞLIĞI MERKEZİNE MERKEZİ HEKİM RANDEVU SİSTEMİYLE YAPILAN BAŞVURULARIN DEĞERLENDİRİLMESİ: BİR MÜDAHALE ÇALIŞMASI
(Nobelmedicus, 2022)Objective: In this study, it was aimed to evaluate the applications made through the Central Physician Appointment System(CPAS) to a family health center. Material and Method: The target population of the intervention study ... -
Comparison of syphilis seropositivity between non-immigrant and immigrant populations in the Anatolian side of Istanbul, Turkiye: Results of five-years retrospective study
(Health Directorate of Istanbul, 2022)Objective: Our study aimed to evaluate the seropositivity for syphilis in non- immigrant and immigrant populations and compare the results regarding demographic data. Methods: In accordance with the reverse algorithm, ... -
A potent ion channel blocker, hydroquinidine, exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells
(Springer Science and Business Media B.V., 2023)Background: Despite recent advances in drug discovery, cancer is still one of the most lethal health problems worldwide. In most cases, standard therapy methods and multi-modal treatments fail, and new therapeutic approaches ... -
Mortality in psoriatic arthritis patients, changes over time, and the impact of COVID-19: results from a multicenter Psoriatic Arthritis Registry (PsART-ID)
(Springerlink, 2023)Background: This study aimed to assess the mortality of PsA before and during the COVID-19 pandemic. Methods: From the prospective, multicenter PsART-ID (Psoriatic Arthritis Registry-International Database), patients from ...
