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dc.contributor.authorVarol, Mehmet
dc.date.accessioned2020-11-20T16:50:24Z
dc.date.available2020-11-20T16:50:24Z
dc.date.issued2020
dc.identifier.issn1064-3745
dc.identifier.urihttps://doi.org/10.1007/7651_2019_260
dc.identifier.urihttps://hdl.handle.net/20.500.12809/6247
dc.descriptionPubMed ID: 31392587en_US
dc.description.abstractPhotodynamic therapy is a promising, minimally invasive, and clinically approved treatment strategy that destroys the cell components by oxidizing the biological molecules such as nucleic acids, carbohydrates, proteins, and lipids, and leads apoptosis in the cells of the target tissue through the generation of singlet oxygen and reactive oxygen species (ROS) owing to the synergic interactions of a nontoxic photosensitizer, a non-thermal light source, and tissue oxygen. This innovative method has drawn the attention of many scientists and been employed in a wide range of medical fields that covers the treatment of cancer diseases and precancerous dermatological disorders, and the aesthetic and cosmetic practices, including photorejuvenation and treatment of photoaging, hirsutism, facial flat warts, rosacea, acne vulgaris, and sebaceous gland hyperplasia. It was therefore intended to provide an in vitro photodynamic therapy assay protocol on human healthy keratinocytes and epidermoid carcinomas to investigate comparatively the therapeutic and destructive activities of the potent light-sensitive medications. © Springer Science+Business Media New York 2019.en_US
dc.item-language.isoengen_US
dc.publisherHumana Press Inc.en_US
dc.item-rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCutaneous squamous cell carcinomaen_US
dc.subjectFluenceen_US
dc.subjectFluence rateen_US
dc.subjectHuman epidermoid carcinomaen_US
dc.subjectHuman keratinocyteen_US
dc.subjectIrradiationen_US
dc.subjectPhotodynamic therapyen_US
dc.subjectPhotosensitizeren_US
dc.subjectSkin canceren_US
dc.subjectVisible lighten_US
dc.titlePhotodynamic therapy assayen_US
dc.item-typebookParten_US
dc.contributor.departmentMÜ, Fen Fakültesi, Moleküler Biyoloji Ve Genetik Bölümüen_US
dc.contributor.institutionauthorVarol, Mehmet
dc.identifier.doi10.1007/7651_2019_260
dc.identifier.volume2109en_US
dc.identifier.startpage241en_US
dc.identifier.endpage250en_US
dc.relation.journalMethods in Molecular Biologyen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US


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