Cellular targets and molecular activity mechanisms of bee venom in cancer: recent trends and developments
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Date
2022Author
Varol, AyşegülSezen, Serap
Evcimen, Dilhan
Zarepour, Atefeh
Ulus, Gönül
Zarrabi, Ali
Orbayoğlu, Asya Gülistan
Varol, Mehmet
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Ayşegül Varol, Serap Sezen, Dilhan Evcimen, Atefeh Zarepour, Gönül Ulus, Ali Zarrabi, Gamal Badr, Sevgi Durna Daştan, Asya Gülistan Orbayoğlu, Zeliha Selamoğlu & Mehmet Varol (2022) Cellular targets and molecular activity mechanisms of bee venom in cancer: recent trends and developments, Toxin Reviews, DOI: 10.1080/15569543.2021.2024576Abstract
Bee venom therapy is known as a traditional approach to curing many medical conditions such as arthritis, pain and rheumatism. Bee venom also provides promising potential for treating many cancers such as breast, lung, ovary, stomach, kidney, prostate, cervical, colon and esophageal cancers, osteosarcoma, leukemia, melanoma and hepatocellular carcinoma. We therefore focused not only on the molecular activity mechanisms and cellular targets of bee venom and its components, but also on modern solutions as cutting-edge nanotechnological advances to overcome existing bottlenecks, and the latest advances in the anticancer application of bee venom in clinical settings.