Yazar "Kara, Murat" için listeleme
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IGF2BP2 gene polymorphism in patients with morbid obesity
Kargün, Kürşat; Şenol, Sefa; Kırkıl, Cüneyt; Çambay, Zafer; Kara, Murat; Aygen, Erhan; Yılmaz, Mustafa (Allied Acad, 2017)Background/Aim: In this study, it was aimed to determine the relationship between morbid obesity and insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) rs1470579 and rs4402960 gene polymorphisms. Materials and ... -
IGF2BP2 gene polymorphism in patients with psoriasis
Kargun, Kursat; Demir, Betul; Çiçek, Demet; Kara, Murat; Bilik, Leyla; Kaya, Haktan (Scientific Publishers of India, 2017)Psoriasis is a chronic inflammatory disease with genetic transmission, the etiology of which has not been completely clarified yet. Insulin-like Growth Factor Binding Protein 2 (IGF2BP2) plays a role in growth, development, ... -
IGF2BP2 gene polymorphism in patients with psoriasis.
Kargun, Kursat; Demir, Betul; Cicek, Demet; Kara, Murat; Bilik, Leyla; Kaya, Haktan (Allied Acad, 2017)Psoriasis is a chronic inflammatory disease with genetic transmission, the etiology of which has not been completely clarified yet. Insulin-like Growth Factor Binding Protein 2 (IGF2BP2) plays a role in growth, development, ... -
The IL-33 gene is related to increased susceptibility to systemic sclerosis
Koca, Süleyman Serdar; Pehlivan, Yavuz; Kara, Murat; Alibaz-Öner, Fatma; Öztuzcu, Serdar; Yılmaz, Neslihan; Onat, Ahmet Mesut (Springer Heidelberg, 2016)Systemic sclerosis (SSc) is a chronic inflammatory disease characterized by widespread fibrosis of the skin and several visceral organs. The pro-fibrotic potential of interleukin (IL)-33 has been demonstrated by in both ... -
Influence of omega-3 fatty acid on orthodontic tooth movement in rats: A biochemical, histological, immunohistochemical and gene expression study
Öğrenim, Gözde; Cesur, Mine G.; Önal, Tuna; Kara, Murat; Şirin, Fevziye B.; Yalçın, Gizem D.; İnan, Sevinç (Wiley, 2019)Structured Abstract Objective The aim of this study was to investigate the effects of omega-3 fatty acids on orthodontic tooth movement. Setting and Sample Population For this study, 56 12-week-old adult male Wistar albino ... -
Insecticide imidacloprid influences cognitive functions and alters learning performance and related gene expression in a rat model
Kara, Murat; Yumrutaş, Önder; Demir, Caner F.; Özdemir, Hasan Hüseyin; Bozgeyik, İbrahim; Coşkun, Salih; Bal, Ramazan (Wiley, 2015)The potential toxic effects of several pesticides, including imidacloprid on non-target organisms have not been clearly established. Also, the chronic effects of non-toxic doses on cognitive function in mammals are unknown. ... -
INVESTIGATION OF REELIN RS7341475, RS362691 AND RS12705169 GENE POLYMORPHISMS IN CASES A WITH SUICIDE ATTEMPT
Şahin, Cem; Kara, Murat; Kara, Bilge; Şahin, Nilfer; Beydilli, Halil; Acar, Ethem (Carbone Editore, 2015)Background: Suicidal ideations and behavior is one of the most serious conditions among psychiatric emergencies. Neurobiology and genetics of suicide attracted more interest in subsequent period. Today, studies focus on ... -
İnfertil bir Erkekte t (10; 19) (q11.2; q13.4) Kromozomal Translokasyonu
Kromozomal yeniden düzenlemeler genellikle erkek infertilitesi ile ilişkilidir. Bu makalede 15 yıldır primer infertilite şikayeti olan 34 yaşındaki bir erkek hastayı sunduk. Hastaya sitogenetik ve Y mikrodelesyon çalışması ... -
Kardiyak Anomalisi Olan Down Sendromlu Hastalarda MEF2C Gen Polimorfizminin Araştırılması
Tüylü, Berrin Ayaz; Kara, Murat; Yılmaz, Erdal; Kalkan, Murat; Uğur, Feti Ahmet; Kargün, Kürşat (2017)Amaç: Down Sendromlu çocuklarda miyosit arttırıcı faktör 2C (MEF2C) gen polimorfizmlerinin araştırılması, sağlıklı kontrollerle karşılaştırılması ve Down Sendromunda sık rastlanan kardiyak malformasyonlar arasındaki ... -
Lack of association between increased mitochondrial DNA(4977) deletion and ATP levels of sputum cells from chronic obstructive pulmonary disease patients versus healthy smokers
Karimova, A.; Oltulu, Y. M.; Azaklı, H.; Kara, Murat; Ustek, D.; Tutluoglu, B.; Onaran, I. (Taylor & Francis Ltd, 2017)In this study we looked at smokers with and without chronic obstructive pulmonary disease (COPD) patients in order to evaluate the incidence of 4977 base pair (bp) mtDNA (mtDNA(4977)) deletion and mtDNA copy number in ... -
Low prevalence of obesity in Behçet's disease is associated with high obestatin level
Koca, Süleyman Serdar; Kara, Murat; Özgen, Metin; Dayanan, Ramazan; Demir, Caner Feyzi; Aksoy, Kader; Işık, Ahmet (2017)Objective: Chronic inflammatory diseases are associated with altered body composition. Ghrelin has anti-inflammatory effects, and its level is altered in obesity and inflammatory diseases. The aim of the study was to ... -
Methylation of cation-chloride cotransporters NKCC1 and KCC2 in patients with juvenile myoclonic epilepsy
Genç, Fatma; Kara, Murat; Ünal, Yasemin; Küçükseymen, Elif Uygur; Gömceli, Yasemin Biçer; Kaynar, Taner; Kutlu, Gülnihal (Springer-Verlag Italia Srl, 2019)The etiology of juvenile myoclonic epilepsy (JME) is still unknown and the process of elaboration of multiple genetic mechanisms is ongoing. The aim of this study was to investigate the potential role of NKCC1 (SCL12A2) ... -
THE METHYLATION STATUS OF NKCC1 AND KCC2 IN THE PATIENTS WITH REFRACTORY TEMPORAL LOBE EPILEPSY
Ünal, Yasemin; Kara, Murat; Genç, Fatma; Aslan Öztürk, Dilek; Biçer Gömceli, Yasemin; Kaynar, Toner; Kutlu, Gülnihal (Literatura Medica, 2019)Purpose - Methylation is a key epigenetic modification of DNA and regarding its impact on epilepsy, it is argued that "DNA methylation may play an important role in seizure susceptibility and maintenance of the disorder". ... -
MTUS1 and its targeting miRNAs in colorectal carcinoma: significant associations
Ozcan, Onder; Kara, Murat; Yumrutas, Onder; Bozgeyik, Esra; Bozgeyik, Ibrahim; Celik, Ozgur Ilhan (Sage Publications Ltd, 2016)Deregulated microRNA (miRNA) expression has been shown to be involved in the pathogenesis of several types of cancers including colorectal cancer (CRC). Thus, determining miRNA targets of genes that play critical role in ... -
MTUS1 tumor suppressor and its miRNA regulators in breast cancer
Kara, Murat; Kaplan, Mehmet; Bozgeyik, İbrahim; Özcan, Önder; Çelik, Özgür İlhan; Bozgeyik, Esra; Yumrutaş, Önder (Elsevier Science Bv, 2016)Breast cancer is major public health problem predominantly effects female population. Current therapeutic approaches to deal with breast cancer are still lack of effectiveness. Thus, identifying/developing novel strategies ... -
Multiple Myeloma Emerging After Chemotherapy for Breast Cancer: Case Presentation and a Brief Review
Gürel, Ali; Aygen, Bilge; Kara, Murat; Tamer, Emin Elkiran (2015)Meme kanseri kadınlarda en sık görülen kanser türüdür. Multipl myelom ise tek hücre tipi kökenli plazma hücrelerinin aşırı çoğalması karakterli bir hastalıktır. Literatürde kemoterapiye ikincil bir çok malignite bildirilmiştir. ... -
Paraoxonase-1 gene in patients with chronic obstructive pulmonary disease investigation Q192R and L55M polymorphisms
Gurbuz, Sukru; Yildiz, Mustafa; Kara, Murat; Kargun, Kursat; Gurger, Mehtap; Atescelik, Metin; Alatas, Omer Dogan (Zhejiang Univ Sch Medicine, 2015)BACKGROUND: The effect of increased oxidative stress on the development of chronic obstructive pulmonary disease (COPD) is well known. One of the antioxidative systems against oxidative stress in human body is paraoxonase ... -
Polymorphisms in ADAMTS4 and ADAMTS5 are not linked to susceptibility to knee osteoarthritis in the Turkish population
Canbek, Umut; İmerci, Ahmet; Kara, Murat; Akgün, Ulaş; Canbek, T. D.; Aydoğan, Nevres Hürriyet (Funpec-Editora, 2016)Considering the functions of aggrecanase-1 (ADAMTS4) and -2 (ADAMTS5), which are thought to be the two major enzymes responsible for the destruction of aggrecans in arthritic diseases, we investigated whether important ... -
Protective effects of vitamin C and vitamin E against hysterosalpingography-induced epithelial degeneration and proliferation in rat endometrium
Pala, Şehmus; Atılgan, Remzi; Kuloğlu, Tuncay; Kara, Murat; Başpınar, Melike; Can, Behzat; Artaş, Gökhan (Dove Medical Press Ltd, 2016)Aim: The aim of this study was to examine the protective effects of vitamin C (VC) and vitamin E (VE) against hysterosalpingography (HSG)-induced epithelial degeneration and proliferation in rat endometrium. Materials and ... -
Reelin Gen rs7341475 Polimorfizmi Auralı Migrenle İlişkilidir
Kara, Bilge; Özdemir, Ebru Marzioğlu; Kara, Murat; Özdemir, Gökhan; Sözen, Ayşe; Kargün, Kürşat (2016)Amaç: Bu çalışmada auralı migren hastalarında Reelin gen polimorfizmleri incelenerek, Reelin gen ile migren hastalığı arasındaki ilişki araştırıldı. Migren vasküler baş ağrıları içinde en sık görülen, genetik ve çevresel ...