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dc.contributor.authorGürsoy, Canan
dc.contributor.authorGürsoy, Güven
dc.contributor.authorGümüş Demirbilek, Semra
dc.date.accessioned2022-08-25T06:16:07Z
dc.date.available2022-08-25T06:16:07Z
dc.date.issued2022en_US
dc.identifier.citationGürsoy C, Gürsoy G, Demirbilek SG. C-reactive protein-albumin ratio and procalcitonin in predicting intensive care unit mortality in traumatic brain injury. Acute Crit Care. 2022 Aug 5. doi: 10.4266/acc.2022.00052. Epub ahead of print. PMID: 35977896.en_US
dc.identifier.issn2586-6060
dc.identifier.urihttps://doi.org/10.4266/acc.2022.00052
dc.identifier.urihttps://hdl.handle.net/20.500.12809/10234
dc.description.abstractBackground: Prediction of intensive care unit (ICU) mortality in traumatic brain injury (TBI), which is a common cause of death in children and young adults, is important for injury management. Neuroinflammation is responsible for both primary and secondary brain injury, and C-reactive protein-albumin ratio (CAR) has allowed use of biomarkers such as procalcitonin (PCT) in predicting mortality. Here, we compared the performance of CAR and PCT in predicting ICU mortality in TBI. Methods: Adults with TBI were enrolled in our study. The medical records of 82 isolated TBI patients were reviewed retrospectively. Results: The mean patient age was 49.0 ± 22.69 years; 59 of all patients (72%) were discharged, and 23 (28%) died. There was a statistically significant difference between PCT and CAR values according to mortality (P<0.05). The area under the curve (AUC) was 0.646 with 0.071 standard error for PCT and 0.642 with 0.066 standard error for CAR. The PCT showed a similar AUC of the receiver operating characteristic to CAR. Conclusion: This study shows that CAR and PCT are usable biomarkers to predict ICU mortality in TBI. When the determined cut-off values are used to predict the course of the disease, the CAR and PCT biomarkers will provide more effective information for treatment planning and for preparation of the family for the treatment process and to manage their outcome expectations.en_US
dc.item-language.isoengen_US
dc.publisherKorean Journal of Critical Care Medicineen_US
dc.relation.isversionof10.4266/acc.2022.00052en_US
dc.item-rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC-reactive protein-albumin ratioen_US
dc.subjectMortalityen_US
dc.subjectProcalcitoninen_US
dc.titleC-reactive protein-albumin ratio and procalcitonin in predicting intensive care unit mortality in traumatic brain injuryen_US
dc.item-typearticleen_US
dc.contributor.departmentMÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.contributor.authorID0000-0003-0658-9138en_US
dc.contributor.authorID0000-0001-8374-7916en_US
dc.contributor.authorID0000-0001-7721-4582en_US
dc.contributor.institutionauthorGürsoy, Canan
dc.contributor.institutionauthorGürsoy, Güven
dc.contributor.institutionauthorGümüş Demirbilek, Semra
dc.relation.journalAcute and Critical Careen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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