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Toplam kayıt 14, listelenen: 1-10
Designing heterocyclic chalcones, benzoyl/sulfonyl hydrazones: An insight into their biological activities and molecular docking study
(Elsevier, 2020)
The aim of this study is to investigate the antioxidant, anticholinesterase and the antiproliferative activities of some chalcones, benzoyl and sulfonyl hydrazones. The antioxidant activity was studied by way of four ...
Design and Bioevaluation of Novel Hydrazide-Hydrazones Derived from 4-Acetyl-N-Substituted Benzenesulfonamide
(Maik Nauka/Interperiodica/Springer, 2020)
In this research, a series of hydrazine-hydrazone derivatives (Ia-g), (IIa-h) were synthesized to discover new antioxidant and anticholinesterase agents. The structures of synthesized compounds were characterized by ...
Pine honey-loaded electrospun poly (vinyl alcohol)/gelatin nanofibers with antioxidant properties
(Taylor & Francis Ltd, 2020)
In this study, bioactive fibers were produced using polyvinyl alcohol (PVA), gelatin and pine honey by using electrospinning method. The influence of honey content (0-15 wt%) on the infrared spectrum, morphology, average ...
Bioactivities and phenolic constituents relationship of Muğla thyme and pine honey of Turkey with the chemometric approach
(Springer, 2021)
The chemical ingredients of pine and thyme honey were studied, along with their medicinal activity properties. A method was validated for common honey compounds using LC-TOF/MS to analyze the ingredients. In vitro ...
Microwave-assisted synthesis of new sulfonyl hydrazones, screening of biological activities and investigation of structure-activity relationship
(Springer Birkhauser, 2016)
Sulfonyl hydrazone scaffold and the piperidine rings have important role in medicinal chemistry. This study shows the synthesis of two novel series of sulfonyl hydrazone having piperidine derivatives by condensing benzene ...
Design and Antiproliferative and Antioxidant Activities of Furan-Based Thiosemicarbazides and 1,2,4-Triazoles: Their Structure-Activity Relationship and SwissADME Predictions
(Springer, 2021)
Due to the limited number of drugs in current clinical use, the diverse biological applications of furan
have encouraged the preparation of a wide variety of thiosemicarbazide and triazole derivatives for the purpose of ...
New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)
Hydrazones and the piperidine ring containing compounds were considered as beneficial substrates in drug design. Therefore, this study was aimed at the synthesis of new benzoyl hydrazones derived from ethyl 4-oxopiperidi ...
CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OIL OF CITRUS SINENSIS: INTERACTION WITH AMPICILLIN AND FLUCONAZOLE
(EDITURA ACAD ROMANE, 2020)
In the present study, the interactions of essential oil (EO) of Citrus sinensis L. Osbeck with two antibiotics (ampicillin and fluconazole), which are commonly used in the treatment of infections, were investigated. C. ...
Synthesis of benzoyl hydrazones having 4-hydroxy-3,5-dimethoxy phenyl ring, their biological activities, and molecular modeling studies on enzyme inhibition activities
(SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAK, 2021)
Hydrazone compounds such as anticholinesterase, tyrosinase, and urease have high capacity in terms of antioxidant activity and enzyme inhibition activities. In this study, benzoyl hydrazones compounds (7a-7m) were synthesized ...
Synthesis, predictions of drug-likeness, and pharmacokinetic properties of some chiral thioureas as potent enzyme inhibition agents
(SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAK, 2022)
A series of chiral thioureas (1 - 17) were synthesized from and tested for their anticholinesterase, tyrosinase, and urease enzyme inhibitor activities. Various phenylisothiocyanates were added to solution of ??-cysteine ...