Yazar "Kara, Murat" için Dahili Tıp Bilimleri Bölümü Koleksiyonu listeleme
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Application of talcum powder, trichloroacetic acid and silver nitrate in female rats for non-surgical sterilization: evaluation of the apoptotic pathway mRNA and miRNA genes
Yumrutaş, Önder; Kara, Murat; Atılgan, Remzi; Kavak, Salih Burçin; Bozgeyik, İbrahim; Sapmaz, Ekrem (Wiley, 2015)There are several methods used for non-surgical sterilization in birth control including quinacrine, trichloroacetic acid (TCA), erythromycin, tetracycline, silver nitrate and talcum powder. Among these, talcum powder, TCA ... -
Changes in sirtuin 2 and sirtuin 3 mRNA expressions in rheumatoid arthritis
Kara, Murat; Yolbaş, Servet; Şahin, Cem; Koca, Süleyman Serdar (Aves, 2017)Objective: Sirtuins (SIRTs) play a prominent role in metabolism, apoptosis, aging, inflammation, and epigenetics. Inflammation, apoptosis, and epigenetics are pathogenic issues in rheumatoid arthritis (RA). This study aimed ... -
Determination of the effects on learning and memory performance and related gene expressions of clothianidin in rat models
Özdemir, Hasan Hüseyin; Kara, Murat; Yumrutaş, Önder; Üçkardeş, Fatih; Eraslan, Ersen; Demir, Caner F.; Bal, Ramazan (Springer, 2014)Clothianidin (CLO) is one of the pesticides used to protect against insects, and its potential toxic effects on cognitive functions are not clearly known. This study aims to evaluate the possible effects of dose-dependent ... -
Differential Expression and in Silico Functional Analysis of Plasma MicroRNAs in the Pathogenesis of Non-segmental Vitiligo
Demir Pektaş, Suzan; Kara, Murat; Doğan, Gürsoy; Pektaş, Mehmet Bilgehan; Baloğlu, Mehmet Cengiz; Sadi, Gökhan (PMC, 2023)Vitiligo is a disease characterized by acquired depigmentation, white macules, and patches on the skin due to the dysfunction of epidermal melanocytes. In this study, we attempt to profile the microRNA (miRNA) expression ... -
Differential expressions of cancer-associated genes and their regulatory miRNAs in colorectal carcinoma
Kara, Murat; Yumrutaş, Önder; Özcan, Önder; Çelik, Özgür İlhan; Bozgeyik, Esra; Bozgeyik, İbrahim; Taşdemir, Şener (Elsevier Science Bv, 2015)Colorectal cancer is one of the frequently seen malignancies in the world. To date, several oncogenes and tumor suppressor genes have been identified and linked to colorectal cancer pathogenesis. Although recent advances ... -
Ectodermal dysplasia-skin fragility syndrome with a new mutation
Alataş, Emine Tuğba; Kara, Asude; Kara, Murat; Doğan, Gürsoy; Baysal, Onur (Wolters Kluwer Medknow Publications, 2017) -
Endothelin-1 Lys198Asn and rs10478694 polymorphism in ischemic stroke
Aslan, Orhan; Gurger, Mehtap; Atescelik, Metin; Kara, Murat; Sen, Askin; Alataş, Ömer Doğan; Kargun, Kursat (Scientific Publishers of India, 2017)Objective: In this study, we aimed to investigate the relationship between ischemic cerebrovascular diseases and Lys198Asn and rs10478694 polymorphism of Endothelin-1 gene, a strong vasoconstrictor. Materials and Methods: ... -
Endothelin-1 Lys198Asn and rs10478694 polymorphism in ischemic stroke.
Aslan, Orhan; Gurger, Mehtap; Atescelik, Metin; Kara, Murat; Sen, Askin; Alatas, Omer Dogan; Kargun, Kursat (Scientific Publishers India, 2017)Objective: In this study, we aimed to investigate the relationship between ischemic cerebrovascular diseases and Lys198Asn and rs10478694 polymorphism of Endothelin-1 gene, a strong vasoconstrictor. Materials and Methods: ... -
Evaluation of RELN gene polymorphism in children with autism spectrum disorder
Şahin, Nilfer; Kara, Murat; Kara, Bilge; Topal, Hatice (Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2018)Objective: With increasing frequency of autism spectrum disorder (ASD) in recent years, etiology has not yet been fully elucidated. Multiple hypotheses have been proposed to explain autism etiology including genetic, ... -
IGF2BP2 gene polymorphism in patients with psoriasis
Kargun, Kursat; Demir, Betul; Çiçek, Demet; Kara, Murat; Bilik, Leyla; Kaya, Haktan (Scientific Publishers of India, 2017)Psoriasis is a chronic inflammatory disease with genetic transmission, the etiology of which has not been completely clarified yet. Insulin-like Growth Factor Binding Protein 2 (IGF2BP2) plays a role in growth, development, ... -
IGF2BP2 gene polymorphism in patients with psoriasis.
Kargun, Kursat; Demir, Betul; Cicek, Demet; Kara, Murat; Bilik, Leyla; Kaya, Haktan (Allied Acad, 2017)Psoriasis is a chronic inflammatory disease with genetic transmission, the etiology of which has not been completely clarified yet. Insulin-like Growth Factor Binding Protein 2 (IGF2BP2) plays a role in growth, development, ... -
Influence of omega-3 fatty acid on orthodontic tooth movement in rats: A biochemical, histological, immunohistochemical and gene expression study
Öğrenim, Gözde; Cesur, Mine G.; Önal, Tuna; Kara, Murat; Şirin, Fevziye B.; Yalçın, Gizem D.; İnan, Sevinç (Wiley, 2019)Structured Abstract Objective The aim of this study was to investigate the effects of omega-3 fatty acids on orthodontic tooth movement. Setting and Sample Population For this study, 56 12-week-old adult male Wistar albino ... -
Insecticide imidacloprid influences cognitive functions and alters learning performance and related gene expression in a rat model
Kara, Murat; Yumrutaş, Önder; Demir, Caner F.; Özdemir, Hasan Hüseyin; Bozgeyik, İbrahim; Coşkun, Salih; Bal, Ramazan (Wiley, 2015)The potential toxic effects of several pesticides, including imidacloprid on non-target organisms have not been clearly established. Also, the chronic effects of non-toxic doses on cognitive function in mammals are unknown. ... -
INVESTIGATION OF REELIN RS7341475, RS362691 AND RS12705169 GENE POLYMORPHISMS IN CASES A WITH SUICIDE ATTEMPT
Şahin, Cem; Kara, Murat; Kara, Bilge; Şahin, Nilfer; Beydilli, Halil; Acar, Ethem (Carbone Editore, 2015)Background: Suicidal ideations and behavior is one of the most serious conditions among psychiatric emergencies. Neurobiology and genetics of suicide attracted more interest in subsequent period. Today, studies focus on ... -
Low prevalence of obesity in Behçet's disease is associated with high obestatin level
Koca, Süleyman Serdar; Kara, Murat; Özgen, Metin; Dayanan, Ramazan; Demir, Caner Feyzi; Aksoy, Kader; Işık, Ahmet (2017)Objective: Chronic inflammatory diseases are associated with altered body composition. Ghrelin has anti-inflammatory effects, and its level is altered in obesity and inflammatory diseases. The aim of the study was to ... -
Methylation of cation-chloride cotransporters NKCC1 and KCC2 in patients with juvenile myoclonic epilepsy
Genç, Fatma; Kara, Murat; Ünal, Yasemin; Küçükseymen, Elif Uygur; Gömceli, Yasemin Biçer; Kaynar, Taner; Kutlu, Gülnihal (Springer-Verlag Italia Srl, 2019)The etiology of juvenile myoclonic epilepsy (JME) is still unknown and the process of elaboration of multiple genetic mechanisms is ongoing. The aim of this study was to investigate the potential role of NKCC1 (SCL12A2) ... -
THE METHYLATION STATUS OF NKCC1 AND KCC2 IN THE PATIENTS WITH REFRACTORY TEMPORAL LOBE EPILEPSY
Ünal, Yasemin; Kara, Murat; Genç, Fatma; Aslan Öztürk, Dilek; Biçer Gömceli, Yasemin; Kaynar, Toner; Kutlu, Gülnihal (Literatura Medica, 2019)Purpose - Methylation is a key epigenetic modification of DNA and regarding its impact on epilepsy, it is argued that "DNA methylation may play an important role in seizure susceptibility and maintenance of the disorder". ... -
The relationship between gestational diabetes mellitus and selenoprotein-P plasma 1 (SEPP1) gene polymorphisms
Akbaba, Gülhan; Akbaba, Eren; Şahin, Cem; Kara, Murat (Taylor & Francis Ltd, 2018)Our aim is to demonstrate any correlation between gestational diabetes mellitus (GDM) and polymorphism of the selenoprotein P (SEPP1) gene encoding the SEPP1 protein, having a role in the insulin resistance in GDM. Forty ... -
Serum adropin level and ENHO gene expression in systemic sclerosis
Yolbaş, Servet; Kara, Murat; Yılmaz, Musa; Aydın, Süleyman; Koca, Süleyman Serdar (Springer London Ltd, 2016)Adropin, a secreted protein, is encoded by the energy homeostasis associated (ENHO) gene. It has been implicated in the several physiological and pathological processes such as angiogenesis and apoptosis. Therefore, the ...