Yazar "Sıcak, Yusuf" için Kimya Bölümü Koleksiyonu listeleme
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Design, in Silico Studies and Biological Evaluation of New Chiral Thiourea and 1,3-Thiazolidine-4,5-dione Derivatives
Evyapan, Samet; Oruç-Emre, Emine Elçin; Sıcak, Yusuf; Karaküçük-İyidoğan, Ayşegül; Öztürk, Mehmet; Yılmaz Tatar, Gizem (John Wiley and Sons Inc, 2023)In this study, new chiral thiourea and 1,3-thiazolidine-4,5-dione derivatives were synthesized, it was aimed to evaluate the various biological activities and molecular docking of these compounds. Firstly, the new thioureas ... -
Designing heterocyclic chalcones, benzoyl/sulfonyl hydrazones: An insight into their biological activities and molecular docking study
Aktar, Bedriye Seda Kursun; Sıcak, Yusuf; Tok, Tugba Taskin; Oruc-Emre, Emine Elcin; Yaglioglu, Ayse Sahin; Iyidogan, Aysegul Karakucuk; Demirtas, Ibrahim; Öztürk, Mehmet (Elsevier, 2020)The aim of this study is to investigate the antioxidant, anticholinesterase and the antiproliferative activities of some chalcones, benzoyl and sulfonyl hydrazones. The antioxidant activity was studied by way of four ... -
Novel fluorine-containing chiral hydrazide-hydrazones: Design, synthesis, structural elucidation, antioxidant and anticholinesterase activity, and in silico studies
Sıcak, Yusuf; Oruç-Emre, Emine Elçin; Öztürk, Mehmet; Taskın-Tok, Tuğba; Karaküçük-İyidoğan, Ayşegül (Wiley, 2019)In this study, a series of fluorine-containing chiral hydrazide-hydrazone derivatives [III-XII] from x29f; -cysteine ethyl ester hydrochloride was synthesized as new antioxidant and anticholinesterase agents. The antioxidant ... -
Synthesis of novel chiral metal complexes derived from chiral thiosemicarbazide ligands as potential antioxidant agents
Basaran, Eyüp; Sıcak, Yusuf; Soğukömeroğulları, Hatice Gamze; Karaküçük-İyidoğan, Ayşegül; Oruç-Emre, Emine Elcin; Sönmez, Mehmet; Öztürk, Mehmet (Wiley, 2019)Two new chiral thiosemicarbazide ligands and their Cu (II), Ni (II), Pd (II), and Zn (II) complexes were synthesized and characterized by nuclear magnetic resonance (NMR) (only for ligand), Fourier transform infrared ... -
Synthesis, Characterization and Biological Evaluation of Novel Thiourea Derivatives
Tok, Fatih; Çakır, Cansel; Çam, Dilaycan; Kırpat, Mustafa Murat; Sıcak, Yusuf (Marmara Üniversitesi, 2022)Objective: A new series of 4-[3-(substitutedphenyl)thioureido]-N-(6-chloropyrazin-2-yl)benzenesulfonamide were synthesized from sulfaclozine. Methods: All compounds were characterized by IR, 1H-NMR spectroscopic methods ... -
Synthesis, characterization, and antioxidant and anticholinesterase activities of pyrazolo derivatives
Sıcak, Yusuf; Oruç Emre, Emine E.; Öztürk, Mehmet; Karakucuk İyidoğan, Ayşegül; Nadeem, Said (Wiley, 2020)Twenty-four pyrazolo derivatives (1-4)(a-f) were synthesized and characterized by FTIR, H-1, and C-13 NMR (Nuclear Magnetic Resonance), and elemental analysis. The synthesized compounds were also investigated for their ...